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FOXP3 Antikörper (N-Term)

FOXP3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Pferd, Kaninchen, Schaf, Hund, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777561
  • Target Alle FOXP3 Antikörper anzeigen
    FOXP3 (Forkhead Box P3 (FOXP3))
    Bindungsspezifität
    • 16
    • 15
    • 12
    • 10
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 143
    • 123
    • 49
    • 26
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Schwein, Pferd, Kaninchen, Schaf, Hund, Meerschweinchen
    Wirt
    • 95
    • 67
    • 20
    • 2
    Kaninchen
    Klonalität
    • 96
    • 88
    Polyklonal
    Konjugat
    • 89
    • 15
    • 11
    • 10
    • 7
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser FOXP3 Antikörper ist unkonjugiert
    Applikation
    • 112
    • 88
    • 55
    • 40
    • 33
    • 27
    • 27
    • 17
    • 16
    • 16
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    PHFMHQLSTV DAHARTPVLQ VHPLESPAMI SLTPPTTATG VFSLKARPGL
    Homologie
    Cow: 100%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 86%, Sheep: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against FOXP3. It was validated on Western Blot and immunohistochemistry.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP3
    Top Product
    Discover our top product FOXP3 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 431 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kawabata, Ohta, Seiler, Pyle, Ishiguro, Zhang, Becker, Troyer, Tamura: "Naïve rat umbilical cord matrix stem cells significantly attenuate mammary tumor growth through modulation of endogenous immune responses." in: Cytotherapy, Vol. 15, Issue 5, pp. 586-97, (2013) (PubMed).

    Takahata, Nomura, Takada, Ohga, Furuno, Hikino, Nakayama, Sakaguchi, Hara: "CD25+CD4+ T cells in human cord blood: an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene." in: Experimental hematology, Vol. 32, Issue 7, pp. 622-9, (2004) (PubMed).

  • Target
    FOXP3 (Forkhead Box P3 (FOXP3))
    Andere Bezeichnung
    FOXP3 (FOXP3 Produkte)
    Hintergrund
    Forkhead box protein P3 (FOXP3, Scurfin, Zinc finger protein JM2) encodes a novel member of the forkhead family of transcription factors. It presumably represses transcription, playing a paramount role in determining the amplitude of the response of CD4 T cells to activation
    Alias Symbols: JM2, AIID, IPEX, PIDX, XPID, DIETER
    Protein Interaction Partner: PRR20A, RBPMS, STUB1, UBC, HSPA1A, IKZF3, GATA3, RUNX1, RELA, NFATC1, HIST1H1B, HDAC1, KAT8, REL, IKZF4, NFAT5, NFATC2, HDAC4, HDAC2, HDAC7, KAT5, HDAC9,
    Protein Size: 431
    Molekulargewicht
    47 kDa
    Gen-ID
    50943
    NCBI Accession
    NM_014009, NP_054728
    UniProt
    Q9BZS1
    Pathways
    Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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