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FOXP3 Antikörper (N-Term)

Name: FOXP3 Antikörper (N-Term)
SKU: ABIN2777561
Price: 470.22 EUR
Availability: InStock

FOXP3 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Pferd, Kaninchen, Schaf, Hund, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated

WB Suggested Anti-FOXP3 Antibody Titration: 5. (FOXP3 Antikörper (N-Term))

IHC

Sample Type: Mouse Spleen frozen with positive lymphocytes/ HPF (x400)Primary Dilution: 1:100Secondary Antibody: Vector Lab Goat Biotin-Conjugated Anti-Rabbit IgGSecondary Dilution: 1:100Image Submitted By: Atsushi Kawabata at Kansas State University (FOXP3 Antikörper (N-Term))

IHC

Host: Rabbit Target Name: FOXP3 Sample Tissue: Human NCI-H226 Antibody Dilution: 1. (FOXP3 Antikörper (N-Term))

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN2777561

Datenblatt (PDF)

Target Alle FOXP3 Antikörper anzeigen

FOXP3 (Forkhead Box P3 (FOXP3))
Bindungsspezifität
16

15

12

10

6

6

6

5

5

4

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reaktivität
143

123

49

26

5

2

1

1

1

1

1

1

1
Human, Maus, Ratte, Rind (Kuh), Schwein, Pferd, Kaninchen, Schaf, Hund, Meerschweinchen
Wirt
95

67

20

2
Kaninchen
Passende Sekundärantikörper
Klonalität
96

88
Polyklonal
Konjugat
89

15

11

10

7

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1
Dieser FOXP3 Antikörper ist unkonjugiert
Applikation
112

88

55

40

33

27

27

17

16

16

8

7

7

6

4

3

2

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz

PHFMHQLSTV DAHARTPVLQ VHPLESPAMI SLTPPTTATG VFSLKARPGL

Homologie

Cow: 100%, Dog: 79%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 86%, Rat: 86%, Sheep: 100%

Produktmerkmale

This is a rabbit polyclonal antibody against FOXP3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung

Protein A purified

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human FOXP3

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anti-Forkhead Box P3 (FOXP3) (AA 191-412) antibody
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anti-Forkhead Box P3 (FOXP3) (C-Term) antibody
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anti-Forkhead Box P3 (FOXP3) (AA 191-412) antibody
FOXP3 Reaktivität: Human WB, IHC, IP, ICC Wirt: Maus Monoclonal C1 unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 283-311), (C-Term) antibody
FOXP3 Reaktivität: Human, Maus WB, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB17111 unconjugated

anti-Forkhead Box P3 (FOXP3) antibody (APC)
FOXP3 Reaktivität: Human, Maus FACS Wirt: Maus Monoclonal 3G3 APC

anti-Forkhead Box P3 (FOXP3) (AA 1-431) antibody
FOXP3 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Forkhead Box P3 (FOXP3) (AA 101-431) antibody
FOXP3 Reaktivität: Human, Maus, Ratte IHC (p) Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Optimal working dilutions should be determined experimentally by the investigator.

Kommentare

Antigen size: 431 AA

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Kawabata, Ohta, Seiler, Pyle, Ishiguro, Zhang, Becker, Troyer, Tamura: "Naïve rat umbilical cord matrix stem cells significantly attenuate mammary tumor growth through modulation of endogenous immune responses." in: Cytotherapy, Vol. 15, Issue 5, pp. 586-97, (2013) (PubMed).

Takahata, Nomura, Takada, Ohga, Furuno, Hikino, Nakayama, Sakaguchi, Hara: "CD25+CD4+ T cells in human cord blood: an immunoregulatory subset with naive phenotype and specific expression of forkhead box p3 (Foxp3) gene." in: Experimental hematology, Vol. 32, Issue 7, pp. 622-9, (2004) (PubMed).
Target

FOXP3 (Forkhead Box P3 (FOXP3))

Andere Bezeichnung

FOXP3 (FOXP3 Produkte)

Hintergrund

Forkhead box protein P3 (FOXP3, Scurfin, Zinc finger protein JM2) encodes a novel member of the forkhead family of transcription factors. It presumably represses transcription, playing a paramount role in determining the amplitude of the response of CD4 T cells to activation
Alias Symbols: JM2, AIID, IPEX, PIDX, XPID, DIETER
Protein Interaction Partner: PRR20A, RBPMS, STUB1, UBC, HSPA1A, IKZF3, GATA3, RUNX1, RELA, NFATC1, HIST1H1B, HDAC1, KAT8, REL, IKZF4, NFAT5, NFATC2, HDAC4, HDAC2, HDAC7, KAT5, HDAC9,
Protein Size: 431

Molekulargewicht

47 kDa

Gen-ID

50943

NCBI Accession

NM_014009, NP_054728

UniProt

Q9BZS1

Pathways

Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation