T-Box 22 Antikörper (Middle Region)

Produktnummer ABIN2777562

Produktdetails anti-T-Box 22 Antikörper

Target: T-Box 22 (TBX22)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser T-Box 22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QSMHKYKPRV HVIEQGSSVD LSQIQSLPTE GVKTFSFKET EFTTVTAYQN

Homologie: Cow: 86%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TBX22. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX22

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 520 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-T-Box 22 Antikörper (ABIN2777562)

Suphapeetiporn, Tongkobpetch, Siriwan, Shotelersuk: "TBX22 mutations are a frequent cause of non-syndromic cleft palate in the Thai population." in: Clinical genetics, Vol. 72, Issue 5, pp. 478-83, (2007) (PubMed).

Details zu T-Box 22

Target: T-Box 22 (TBX22)

Andere Bezeichnung: TBX22 (TBX22 Produkte)

Hintergrund: This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CLPA, TBXX, dJ795G23.1, CPX
Protein Interaction Partner: VENTX, HSP90AA1, APP,
Protein Size: 520

Molekulargewicht: 58 kDa

Gen-ID: 50945

NCBI Accession: NM_016954, NP_058650

UniProt: Q9Y458