HMG20A Antikörper (Middle Region)

Produktnummer ABIN2777572

Produktdetails anti-HMG20A Antikörper

Target: HMG20A (High-Mobility Group 20A (HMG20A))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Pferd, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMG20A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RKTQDRQKGK SHRQDAARQA THDHEKETEV KERSVFDIPI FTEEFLNHSK

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HMG20A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HMG20A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 347 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HMG20A

Target: HMG20A (High-Mobility Group 20A (HMG20A))

Andere Bezeichnung: HMG20A (HMG20A Produkte)

Hintergrund: HMG20A plays a role in neuronal differentiation as chromatin-associated protein. HMG20A acts as inhibitor of HMG20B. HMG20A overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. HMG20A involved in the recruitment of the histone methyltransferase MLL and consequent increased methylation of histone H3 lysine 4
Alias Symbols: HMGX1, HMGXB1
Protein Interaction Partner: RSPH9, CFAP53, SYTL4, SCNM1, CCDC136, RPP30, HMG20A, PTH2R, KPNA2, HPCAL1, DTNB, FMNL1, ADD1, BRAP, UBC, HECW2, HTT, HDAC2, HDAC1, MTA3, KDM1A, SMAD4, ELAVL1, GTF2A1L, TESC, RBM7, CCNK, MAGOHB,
Protein Size: 347

Molekulargewicht: 40 kDa

Gen-ID: 10363

NCBI Accession: NM_018200, NP_060670

UniProt: Q9NP66