ACSL1 Antikörper (N-Term)

Produktnummer ABIN2777591

Produktdetails anti-ACSL1 Antikörper

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund, Zebrafisch (Danio rerio), Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACSL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: ALLDSDEPLV YFYDDVTTLY EGFQRGIQVS NNGPCLGSRK PDQPYEWLSY

Homologie: Cow: 85%, Dog: 92%, Guinea Pig: 85%, Horse: 79%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 100%, Rat: 85%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against ACSL1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACSL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 698 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ACSL1 Antikörper (ABIN2777591)

Soupene, Kuypers: "Multiple erythroid isoforms of human long-chain acyl-CoA synthetases are produced by switch of the fatty acid gate domains." in: BMC molecular biology, Vol. 7, pp. 21, (2006) (PubMed).

Details zu ACSL1

Target: ACSL1 (Acsl1) (Acyl-CoA Synthetase Long-Chain Family Member 1 (Acsl1))

Andere Bezeichnung: ACSL1 (Acsl1 Produkte)

Synonyme: ACS1 antikoerper, FACL1 antikoerper, FACL2 antikoerper, LACS antikoerper, LACS1 antikoerper, LACS2 antikoerper, Acas antikoerper, Acas1 antikoerper, Acs antikoerper, FACS antikoerper, Facl2 antikoerper, ACS antikoerper, COAA antikoerper, zgc:110081 antikoerper, CER8 antikoerper, ECERIFERUM 8 antikoerper, LONG-CHAIN ACYL-COA SYNTHASE 1 antikoerper, T8I13.8 antikoerper, F13F21.14 antikoerper, F13F21_14 antikoerper, LATERAL ROOT DEVELOPMENT 2 antikoerper, LRD2 antikoerper, long-chain acyl-CoA synthetase 2 antikoerper, acyl-CoA synthetase long chain family member 1 antikoerper, acyl-CoA synthetase long-chain family member 1 antikoerper, acyl-CoA synthetase long chain family member 1a antikoerper, AMP-dependent synthetase and ligase family protein antikoerper, long-chain acyl-CoA synthetase 2 antikoerper, ACSL1 antikoerper, Acsl1 antikoerper, acsl1a antikoerper, LACS1 antikoerper, LACS2 antikoerper

Hintergrund: ACSL1 encodes an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation.The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ACS1, FACL1, FACL2, LACS, LACS1, LACS2
Protein Interaction Partner: SUMO2, PARK2, ATP4A, UBC, NR3C2, ECT2, UBD,
Protein Size: 698

Molekulargewicht: 78 kDa

Gen-ID: 2180

NCBI Accession: NM_001995, NP_001986

UniProt: P33121

Pathways: Regulation of Lipid Metabolism by PPARalpha