Hairless Antikörper (Middle Region)

Produktnummer ABIN2777657

Produktdetails anti-Hairless Antikörper

Target: Hairless (HR)

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hairless Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RVWAPGDAGQ QKESTQKTPP TPQPSCNGDT HRTKSIKEET PDSAETPAED

Homologie: Cow: 77%, Dog: 85%, Human: 100%, Mouse: 77%, Pig: 85%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against HR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1189 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Hairless

Target: Hairless (HR)

Andere Bezeichnung: HR (HR Produkte)

Synonyme: ALUNC antikoerper, AU antikoerper, HSA277165 antikoerper, MUHH antikoerper, MUHH1 antikoerper, HR antikoerper, N antikoerper, ba antikoerper, bldy antikoerper, hr antikoerper, rh antikoerper, rh-bmh antikoerper, rhino antikoerper, HR, lysine demethylase and nuclear receptor corepressor antikoerper, hairless antikoerper, HR antikoerper, Hr antikoerper

Hintergrund: HR is a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases. Mutations in this gene have been documented in cases of autosomal recessive congenital alopecia and atrichia with papular lesions.This gene encodes a protein whose function has been linked to hair growth. A similar protein in rat functions as a transcriptional corepressor for thyroid hormone and interacts with histone deacetylases. Mutations in this gene have been documented in cases of autosomal recessive congenital alopecia and atrichia with papular lesions. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ALUNC, AU, HSA277165, MUHH, MUHH1
Protein Interaction Partner: VDR, TBL1X, TRIM27, RARB, RARA, HDAC1, HDAC5, HDAC3, HMGB1, HDAC2, THRA,
Protein Size: 1189

Molekulargewicht: 127 kDa

Gen-ID: 55806

NCBI Accession: NM_005144, NP_005135

UniProt: O43593