REXO4 Antikörper (C-Term)

Produktnummer ABIN2777669

Produktdetails anti-REXO4 Antikörper

Target: REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Schwein, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REXO4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QYGKCVYDKY VKPTEPVTDY RTAVSGIRPE NLKQGEELEV VQKEVAEMLK

Homologie: Cow: 77%, Dog: 100%, Guinea Pig: 79%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against REXO4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human REXO4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 422 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu REXO4

Target: REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))

Andere Bezeichnung: REXO4 (REXO4 Produkte)

Synonyme: REXO4 antikoerper, REX4 antikoerper, XPMC2 antikoerper, XPMC2H antikoerper, Gm111 antikoerper, Xpmc2h antikoerper, xpmc2 antikoerper, im:7156740 antikoerper, si:ch73-209e20.4 antikoerper, REX4 homolog, 3'-5' exonuclease antikoerper, REX4, 3'-5' exonuclease antikoerper, RNA exonuclease 4 antikoerper, putative 3'-5' exonuclease antikoerper, REXO4 antikoerper, Rexo4 antikoerper, LOC100229203 antikoerper, rexo4.S antikoerper, CAALFM_C112440WA antikoerper, rexo4 antikoerper

Hintergrund: The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
Alias Symbols: REX4, XPMC2, XPMC2H
Protein Interaction Partner: UBC, SIRT7, ESR2, ESR1,
Protein Size: 422

Molekulargewicht: 47 kDa

Gen-ID: 57109

NCBI Accession: NM_020385, NP_065118

UniProt: Q9GZR2