SLC38A2 Antikörper (N-Term)

Produktnummer ABIN2777727

Produktdetails anti-SLC38A2 Antikörper

Target: SLC38A2 (Solute Carrier Family 38, Member 2 (SLC38A2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC38A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AALKSHYADV DPENQNFLLE SNLGKKKYET EFHPGTTSFG MSVFNLSNAI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC38A2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC38A2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 506 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SLC38A2 Antikörper (ABIN2777727)

Hernandez-García, Manjarín, Suryawan, Nguyen, Davis, Orellana: "Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia." in: Pediatric research, Vol. 80, Issue 3, pp. 448-51, (2016) (PubMed).

Suryawan, Nguyen, Almonaci, Davis: "Abundance of amino acid transporters involved in mTORC1 activation in skeletal muscle of neonatal pigs is developmentally regulated." in: Amino acids, Vol. 45, Issue 3, pp. 523-30, (2013) (PubMed).

Details zu SLC38A2

Target: SLC38A2 (Solute Carrier Family 38, Member 2 (SLC38A2))

Andere Bezeichnung: SLC38A2 (SLC38A2 Produkte)

Hintergrund: Under hypertonic conditions the induction of SLC38A2/SNAT2 leads to the stimulation of transport system A and to the increase in the cell content of amino acids. Its amino acid response element, along with a nearby conserved CAAT box, has enhancer activity in that it functions in an orientation and position independent manner, and it confers regulated transcription to a heterologous promoter.
Alias Symbols: ATA2, KIAA1382, PRO1068, SAT2, SNAT2
Protein Interaction Partner: UBC, APP, MCU, FLOT1, COX5A, ELAVL1, STX11,
Protein Size: 506

Molekulargewicht: 56 kDa

Gen-ID: 54407

NCBI Accession: NM_018976, NP_061849

UniProt: Q96QD8

Pathways: Dicarboxylic Acid Transport