ARID4A Antikörper (C-Term)

Produktnummer ABIN2777742

Produktdetails anti-ARID4A Antikörper

Target: ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))

Bindungsspezifität: C-Term

Reaktivität: Human, Hund, Rind (Kuh), Maus, Schwein, Kaninchen, Ratte, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARID4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NSSKCTPVKH LNVSKPQKLA RSPARISPHI KDGEKDKHRE KHPNSSPRTY

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 86%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ARID4A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ARID4A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1257 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ARID4A Antikörper (ABIN2777742)

Kondou, Kawai, Tachikawa, Kimoto, Yamagata, Koinuma, Yamazaki, Nakayama, Mushiake, Ozono, Michigami: "Sodium-coupled neutral amino acid transporter 4 functions as a regulator of protein synthesis during liver development." in: Hepatology research : the official journal of the Japan Society of Hepatology, Vol. 43, Issue 11, pp. 1211-23, (2014) (PubMed).

Details zu ARID4A

Target: ARID4A (AT Rich Interactive Domain 4A (RBP1-Like) (ARID4A))

Andere Bezeichnung: ARID4A (ARID4A Produkte)

Synonyme: wu:fc43f03 antikoerper, wu:fi06c05 antikoerper, wu:fi11g07 antikoerper, wu:fi14h03 antikoerper, zgc:110391 antikoerper, ARID4A antikoerper, rbp1 antikoerper, rbbp1 antikoerper, rbp-1 antikoerper, MGC130902 antikoerper, RBBP-1 antikoerper, RBBP1 antikoerper, RBP-1 antikoerper, RBP1 antikoerper, A630009N03 antikoerper, A630067N03Rik antikoerper, MmRBBP1 antikoerper, Rbbp1 antikoerper, AT rich interactive domain 4A (RBP1-like) antikoerper, AT-rich interaction domain 4A antikoerper, AT-rich interaction domain 4A L homeolog antikoerper, arid4a antikoerper, ARID4A antikoerper, arid4a.L antikoerper, Arid4a antikoerper

Hintergrund: ARID4A encodes a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described.
Alias Symbols: RBP1, RBBP1, RBP-1, RBBP-1
Protein Interaction Partner: SUMO2, SUMO1, HDAC1, BRMS1, HIST2H3C, HIST4H4, UBC, CDK2, CDK1, CCNE1, CCNB1, CCNA2, CCND1, CDK4, SIN3A, SAP30, RB1, SIN3B, RBBP7, RBBP4, ARID4B, HDAC3, EID1, HDAC2, ING2, RBL1,
Protein Size: 1257

Molekulargewicht: 143 kDa

Gen-ID: 5926

NCBI Accession: NM_002892, NP_002883

UniProt: P29374