Diazepam Binding Inhibitor Antikörper (N-Term)

Produktnummer ABIN2777771

Produktdetails anti-Diazepam Binding Inhibitor Antikörper

Target: Diazepam Binding Inhibitor (DBI)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Diazepam Binding Inhibitor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MSQAEFEKAA EEVRHLKTKP SDEEMLFIYG HYKQATVGDI NTERPGMLDF

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 92%, Human: 100%, Mouse: 85%, Rabbit: 86%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against DBI. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DBI

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 87 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Diazepam Binding Inhibitor

Target: Diazepam Binding Inhibitor (DBI)

Andere Bezeichnung: DBI (DBI Produkte)

Synonyme: ACBD1 antikoerper, ACBP antikoerper, CCK-RP antikoerper, EP antikoerper, dbib antikoerper, DBI antikoerper, wu:fb63e10 antikoerper, zgc:56108 antikoerper, zgc:77734 antikoerper, Acbp antikoerper, endozepine antikoerper, Acoabp3 antikoerper, Ep antikoerper, Odn antikoerper, RNACOABP3 antikoerper, Ttn antikoerper, acbd1 antikoerper, acbp antikoerper, cck-rp antikoerper, dbi antikoerper, dbi-a antikoerper, dbi-b antikoerper, dbia antikoerper, diazepam binding inhibitor, acyl-CoA binding protein antikoerper, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) S homeolog antikoerper, diazepam-binding inhibitor antikoerper, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) antikoerper, acyl-CoA-binding protein antikoerper, diazepam binding inhibitor antikoerper, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) L homeolog antikoerper, DBI antikoerper, dbi.S antikoerper, dbi antikoerper, LOC706367 antikoerper, Dbi antikoerper, dbi.L antikoerper

Hintergrund: DBI is diazepam binding inhibitor. The protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. DBI is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ACBD1, ACBP, CCK-RP, EP, MGC70414
Protein Interaction Partner: UBC, MAP1LC3B, NSFL1C, DUSP23, NIPSNAP1, RAD23B, RAD23A, GSK3B, UBXN2A, TSPO, PPCDC,
Protein Size: 87

Molekulargewicht: 10 kDa

Gen-ID: 1622

NCBI Accession: NM_001079862, NP_001073331

UniProt: P07108