SOX6 Antikörper (Middle Region)

Produktnummer ABIN2777776

Produktdetails anti-SOX6 Antikörper

Target: SOX6 (SRY (Sex Determining Region Y)-Box 6 (SOX6))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SOX6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: YGMKTDGGSL AGNEMINGED EMEMYDDYED DPKSDYSSEN EAPEAVSAN

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SOX6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SOX6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 804 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SOX6

Target: SOX6 (SRY (Sex Determining Region Y)-Box 6 (SOX6))

Andere Bezeichnung: SOX6 (SOX6 Produkte)

Synonyme: HSSOX6 antikoerper, SOXD antikoerper, Sox6 antikoerper, AI987981 antikoerper, SOX-LZ antikoerper, fc35a10 antikoerper, fc50e03 antikoerper, sox-lz antikoerper, sox6b antikoerper, wu:fc35a10 antikoerper, wu:fc50e03 antikoerper, SRY-box 6 antikoerper, SRY box 6 antikoerper, SRY (sex determining region Y)-box 6 antikoerper, SOX6 antikoerper, Sox6 antikoerper, sox6 antikoerper

Hintergrund: SOX6 is a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. SOX6 is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. SOX6 interacts with other family members to cooperatively activate gene expression.Members of the SOX gene family, such as SOX6, encode transcription factors defined by the conserved high mobility group (HMG) DNA-binding domain. Unlike most transcription factors, SOX transcription factors bind to the minor groove of DNA, causing a 70- to 85-degree bend and introducing local conformational changes (Cohen-Barak et al., 2001 [PubMed 11255018]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2696 AL136780.1 1-2696 2697-5158 AC009869.7 10394-12855
Alias Symbols: HSSOX6, SOXD
Protein Interaction Partner: TAF4, TRIP12, UBC, SOX2, POMGNT1, ZNF184, UBE2J1, SUMO1, SUMO2, SUMO3, HDAC1, CTNNB1, SOX5, CENPK, DAZAP2, SOX6, CTBP2,
Protein Size: 804

Molekulargewicht: 89 kDa

Gen-ID: 55553

NCBI Accession: NM_017508, NP_059978

UniProt: A8MRT1