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SHOX2 Antikörper (Middle Region)

SHOX2 Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Zebrafisch (Danio rerio), Kaninchen, Pferd WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777840
  • Target Alle SHOX2 Antikörper anzeigen
    SHOX2 (Short Stature Homeobox 2 (SHOX2))
    Bindungsspezifität
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 17
    • 9
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Zebrafisch (Danio rerio), Kaninchen, Pferd
    Wirt
    • 10
    • 7
    Kaninchen
    Klonalität
    • 13
    • 4
    Polyklonal
    Konjugat
    • 17
    Dieser SHOX2 Antikörper ist unkonjugiert
    Applikation
    • 14
    • 8
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    SEARVQVWFQ NRRAKCRKQE NQLHKGVLIG AASQFEACRV APYVNVGALR
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SHOX2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SHOX2
    Top Product
    Discover our top product SHOX2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 331 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SHOX2 (Short Stature Homeobox 2 (SHOX2))
    Andere Bezeichnung
    SHOX2 (SHOX2 Produkte)
    Synonyme
    SHOX2 antikoerper, og12 antikoerper, shot antikoerper, og12x antikoerper, ogi2x antikoerper, OG12 antikoerper, OG12X antikoerper, SHOT antikoerper, 6330543G17Rik antikoerper, Og12x antikoerper, Prx3 antikoerper, zgc:65884 antikoerper, zgc:77344 antikoerper, short stature homeobox 2 antikoerper, SHOX2 antikoerper, shox2 antikoerper, Shox2 antikoerper
    Hintergrund
    SHOX2 is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is a member of the homeo box family of genes that encode proteins containing a 60-amino acid residue motif that represents a DNA binding domain. Homeo box genes have been characterized extensively as transcriptional regulators involved in pattern formation in both invertebrate and vertebrate species. Several human genetic disorders are caused by aberrations in human homeo box genes. SHOX is a pseudoautosomal homeo box gene that is thought to be responsible for idiopathic short stature and implicated to play a role in the short stature phenotype of Turner syndrome patients. This gene is considered to be a candidate gene for Cornelia de Lange syndrome. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified.
    Alias Symbols: OG12, OG12X, OGI2X, SHOT
    Protein Interaction Partner: CDK4, ELAVL1, TRIM29, KDM5B,
    Protein Size: 331
    Molekulargewicht
    35 kDa
    Gen-ID
    6474
    NCBI Accession
    NM_006884, NP_006875
    UniProt
    O60902
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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