SNAIL Antikörper (N-Term)

Produktnummer ABIN2777858

Produktdetails anti-SNAIL Antikörper

Target: SNAIL (SNAI1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNAIL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MPRSFLVRKP SDPNRKPNYS ELQDSNPEFT FQQPYDQAHL LAAIPPPEIL

Homologie: Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SNAI1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SNAI1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 264 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SNAIL Antikörper (ABIN2777858)

He, Lu, Hu, Zhang, Qin, Wang, Xing, Xi, Wang: "The Wnt11 Signaling Pathway in Potential Cellular EMT and Osteochondral Differentiation Progression in Nephrolithiasis Formation." in: International journal of molecular sciences, Vol. 16, Issue 7, pp. 16313-29, (2016) (PubMed).

Sihto, Lundin, Lundin, Lehtimäki, Ristimäki, Holli, Sailas, Kataja, Turpeenniemi-Hujanen, Isola, Heikkilä, Joensuu: "Breast cancer biological subtypes and protein expression predict for the preferential distant metastasis sites: a nationwide cohort study." in: Breast cancer research : BCR, Vol. 13, Issue 5, pp. R87, (2012) (PubMed).

Surati, Robinson, Nandi, Faoro, Demchuk, Rolle, Kanteti, Ferguson, Hasina, Gangadhar, Salama, Arif, Kirchner, Mendonca, Campbell, Limvorasak, Villaflor, Hensing, Krausz, Vokes, Husain, Ferguson et al.: "Proteomic characterization of non-small cell lung cancer in a comprehensive translational thoracic oncology database. ..." in: Journal of clinical bioinformatics, Vol. 1, Issue 8, pp. 1-11, (2011) (PubMed).

Wang, Quah, Dong, Manser, Tang, Zeng: "PRL-3 down-regulates PTEN expression and signals through PI3K to promote epithelial-mesenchymal transition." in: Cancer research, Vol. 67, Issue 7, pp. 2922-6, (2007) (PubMed).

Details zu SNAIL

Target: SNAIL (SNAI1)

Andere Bezeichnung: SNAI1 (SNAI1 Produkte)

Synonyme: SLUGH2 antikoerper, SNA antikoerper, SNAH antikoerper, SNAIL antikoerper, SNAIL1 antikoerper, dJ710H13.1 antikoerper, AI194338 antikoerper, Sna antikoerper, Sna1 antikoerper, Snail antikoerper, Snail1 antikoerper, SNAI1 antikoerper, BG:DS01845.1 antikoerper, CG3956 antikoerper, Dmel\\CG3956 antikoerper, Sco antikoerper, br28 antikoerper, br29 antikoerper, l(2)35Db antikoerper, l(2)br28 antikoerper, l(2)br29 antikoerper, l(3)br28 antikoerper, l35Db antikoerper, sn antikoerper, Xsnail antikoerper, sna antikoerper, snail1 antikoerper, xSna antikoerper, Snai antikoerper, sna2 antikoerper, snail2 antikoerper, cb643 antikoerper, sna-1 antikoerper, sna1 antikoerper, snai1 antikoerper, snail1a antikoerper, zgc:109820 antikoerper, snail family transcriptional repressor 1 antikoerper, snail family zinc finger 1 antikoerper, snail homolog 1 (Drosophila) antikoerper, snail antikoerper, zinc-finger transcription factor Snail antikoerper, snail family zinc finger 1 S homeolog antikoerper, protein escargot antikoerper, transcription factor protein antikoerper, snail zinc finger protein antikoerper, snail family zinc finger 1b antikoerper, snail family zinc finger 1a antikoerper, SNAI1 antikoerper, Snai1 antikoerper, sna antikoerper, snail antikoerper, snai1.S antikoerper, LOC410464 antikoerper, snai1b antikoerper, snai1a antikoerper

Hintergrund: The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo.
Alias Symbols: SNA, SNAH, SNAIL, SLUGH2, SNAIL1, dJ710H13.1
Protein Interaction Partner: MTUS2, KRT31, TRIM23, ACTN2, MID2, NOTCH2NL, KRTAP10-3, KRT40, FBXL5, EZH2, RNF2, RING1, LATS2, UBC, BTRC, TP53, MDM2, GSK3B, HDAC1, CHD4, KDM1A, HDAC3, HDAC2, RCOR1, FBXL14, NOTCH1, HIST1H3A, EGR1, AJUBA, Sin3a, HOXD4, SUZ12, CTDSP1, CTDSPL, CTDSP2, QRIC
Protein Size: 264

Molekulargewicht: 29 kDa

Gen-ID: 6615

NCBI Accession: NM_005985, NP_005976

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling