Claudin 1 Antikörper (C-Term)

Produktnummer ABIN2778045

Produktdetails anti-Claudin 1 Antikörper

Target: Claudin 1 (CLDN1)

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Hund, Schaf, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: GQALFTGWAA ASLCLLGGAL LCCSCPRKTT SYPTPRPYPK PAPSSGKDYV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CLDN1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 211 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Claudin 1 Antikörper (ABIN2778045)

Coyne, Gambling, Boucher, Carson, Johnson: "Role of claudin interactions in airway tight junctional permeability." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 285, Issue 5, pp. L1166-78, (2003) (PubMed).

Details zu Claudin 1

Target: Claudin 1 (CLDN1)

Andere Bezeichnung: CLDN1 (CLDN1 Produkte)

Synonyme: CLD1 antikoerper, ILVASC antikoerper, SEMP1 antikoerper, AI596271 antikoerper, cldn19 antikoerper, claudin-1 antikoerper, cld1 antikoerper, ilvasc antikoerper, semp1 antikoerper, CLDN1 antikoerper, claudin 1 antikoerper, claudin 1 S homeolog antikoerper, CLDN1 antikoerper, Cldn1 antikoerper, cldn1 antikoerper, cldn1.S antikoerper

Hintergrund: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This protein, a member of the claudin family, is an integral membrane protein and a component of tight junction strands.
Alias Symbols: CLD1, SEMP1, ILVASC
Protein Interaction Partner: UBC, DRG1, LNX1, TJP3, BRD4, MPDZ, TJP2, CLDN1, INADL, CLDN3, WNK4, TJP1, MMP14, MMP2, CLDN5,
Protein Size: 211

Molekulargewicht: 23 kDa

Gen-ID: 9076

NCBI Accession: NM_021101, NP_066924

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C