Pirin Antikörper (C-Term)

Produktnummer ABIN2778062

Produktdetails anti-Pirin Antikörper

Target: Pirin (PIR)

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Pirin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: SHFVLIAGEP LREPVIQHGP FVMNTNEEIS QAILDFRNAK NGFERAKTWK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PIR. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PIR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 290 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Pirin

Target: Pirin (PIR)

Andere Bezeichnung: PIR (PIR Produkte)

Synonyme: ATPIRIN1 antikoerper, PRN1 antikoerper, pirin antikoerper, 2310042L19Rik antikoerper, Pirnl antikoerper, zgc:92778 antikoerper, xpir antikoerper, pirin antikoerper, pirin L homeolog antikoerper, PIR antikoerper, PRN antikoerper, Pir antikoerper, pir antikoerper, pir.L antikoerper

Hintergrund: PIR is a member of the cupin superfamily. The protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication.This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.
Protein Interaction Partner: SMAD9, UBL7, SPEN, SUGT1, STAM, PSMB2, PPP2CA, CLNS1A, ARHGDIA, NFIX, NFKBIA, BCL3,
Protein Size: 290

Molekulargewicht: 32 kDa

Gen-ID: 8544

NCBI Accession: NM_003662, NP_003653

UniProt: O00625