MLL4 Antikörper (N-Term)

Produktnummer ABIN2778080

Produktdetails anti-MLL4 Antikörper

Target: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Saccharomyces cerevisiae, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLL4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: WAGPRVQRGR GRGRGRGWGP SRGCVPEEES SDGESDEEEF QGFHSDEDVA

Homologie: Cow: 92%, Dog: 85%, Guinea Pig: 92%, Horse: 83%, Human: 100%, Mouse: 92%, Rabbit: 92%, Rat: 92%, Yeast: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against MLL4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MLL4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 582 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MLL4

Target: MLL4 (Histone-Lysine N-Methyltransferase MLL4 (MLL4))

Andere Bezeichnung: MLL4 (MLL4 Produkte)

Synonyme: HRX2 antikoerper, MLL1B antikoerper, MLL2 antikoerper, MLL4 antikoerper, TRX2 antikoerper, WBP7 antikoerper, 2610014H22Rik antikoerper, Mll2 antikoerper, Wbp7 antikoerper, mKIAA0304 antikoerper, ALR antikoerper, BC032281 antikoerper, BC058659 antikoerper, C430014K11Rik antikoerper, KMT2B antikoerper, Mll4 antikoerper, RGD1308331 antikoerper, lysine methyltransferase 2B antikoerper, lysine (K)-specific methyltransferase 2B antikoerper, lysine (K)-specific methyltransferase 2D antikoerper, KMT2B antikoerper, Kmt2b antikoerper, Kmt2d antikoerper

Hintergrund: MLL4 a protein which contains multiple domains including a CXXC zinc finger, three PHD zinc fingers, two FY-rich domains, and a SET (suppressor of variegation, enhancer of zeste, and trithorax) domain. The SET domain is a conserved C-terminal domain that characterizes proteins of the MLL (mixed-lineage leukemia) family. MLL4 is ubiquitously expressed in adult tissues. It is also amplified in solid tumor cell lines, and may be involved in human cancer
Alias Symbols: HRX2, MLL2, TRX2, WBP7, MLL4
Protein Interaction Partner: UBC, SMAD3, ZNF512B, ATXN1, HIST2H3C, WDR5, ASH2L, RBBP5, SEPT8, RPP14, NREP, TSC22D1, TK1, SMN1, RAP1B, PIN1, GRB7, RCC1, CDKN1A, ATP1B1, ANXA7, ANXA1, BCL6, WDR82, PAGR1, PAXIP1, NCOA6, SMARCB1, PRPF40A,
Protein Size: 582

Molekulargewicht: 64 kDa

Gen-ID: 9757

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Warburg Effekt