PARP3 Antikörper (C-Term)

Produktnummer ABIN2778113

Produktdetails anti-PARP3 Antikörper

Target: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Pferd, Schwein, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARP3 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Sequenz: LGREHHINTD NPSLKSPPPG FDSVIARGHT EPDPTQDTEL ELDGQQVVVP

Homologie: Cow: 92%, Dog: 91%, Horse: 100%, Human: 100%, Mouse: 77%, Pig: 85%, Rabbit: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against PARP3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PARP3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 532 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PARP3 Antikörper (ABIN2778113)

Augustin, Spenlehauer, Dumond, Ménissier-De Murcia, Piel, Schmit, Apiou, Vonesch, Kock, Bornens, De Murcia: "PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression." in: Journal of cell science, Vol. 116, Issue Pt 8, pp. 1551-62, (2003) (PubMed).

Details zu PARP3

Target: PARP3 (Poly (ADP-Ribose) Polymerase Family, Member 3 (PARP3))

Andere Bezeichnung: PARP3 (PARP3 Produkte)

Synonyme: ADPRT-3 antikoerper, PARP-3 antikoerper, PM38 antikoerper, Adprtl3 antikoerper, fj17c06 antikoerper, wu:fj17c06 antikoerper, zgc:66157 antikoerper, PARP3 antikoerper, parp3 antikoerper, ADPRT3 antikoerper, ADPRTL2 antikoerper, ADPRTL3 antikoerper, ARTD3 antikoerper, IRT1 antikoerper, PADPRT-3 antikoerper, A930002C11Rik antikoerper, AW990611 antikoerper, Adprt3 antikoerper, pADPRT-3 antikoerper, seed maturation protein PM38 antikoerper, poly (ADP-ribose) polymerase family, member 3 antikoerper, poly(ADP-ribose) polymerase family member 3 antikoerper, poly(ADP-ribose) polymerase family member 3 L homeolog antikoerper, PARP3 antikoerper, parp3 antikoerper, parp3.L antikoerper, Parp3 antikoerper

Hintergrund: PARP3 belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. PARP3 is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: IRT1, ADPRT3, ADPRTL2, ADPRTL3, PADPRT-3
Protein Interaction Partner: UBC, APP, PARP3, HIST1H1A, PARP1, HIST2H3C, MTHFD2, HIST2H2BE, RPA3,
Protein Size: 532

Molekulargewicht: 59 kDa

Gen-ID: 10039

NCBI Accession: NM_005485, NP_005476

UniProt: Q9Y6F1