Asialoglycoprotein Receptor 1 Antikörper (N-Term)

Produktnummer ABIN2778132

Produktdetails anti-Asialoglycoprotein Receptor 1 Antikörper

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Saccharomyces cerevisiae, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Asialoglycoprotein Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RKMKSLESQL EKQQKDLSED HSSLLLHVKQ FVSDLRSLSC QMAALQGNGS

Homologie: Cow: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 93%, Rat: 92%, Yeast: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against ASGR1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 291 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Andere Bezeichnung: ASGR1 (ASGR1 Produkte)

Synonyme: ASGR1 antikoerper, ASGPR antikoerper, ASGPR1 antikoerper, CLEC4H1 antikoerper, HL-1 antikoerper, Asgr antikoerper, Asgr-1 antikoerper, ASGR antikoerper, RATRHL1 antikoerper, RHL1 antikoerper, asialoglycoprotein receptor 1 antikoerper, LOC721786 antikoerper, ASGR1 antikoerper, LOC489461 antikoerper, Asgr1 antikoerper, LOC101116157 antikoerper

Hintergrund: ASGR1 encodes for a cell surface receptor binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface.
Alias Symbols: HL-1, ASGPR, ASGPR1, CLEC4H1
Protein Interaction Partner: CERS2, HIVEP1, SYVN1, VKORC1, FBXO6, EDEM1, HSPA5, CANX, APP, CLEC4G, NLK, RBBP6, HSP90B1, TG, HSP90AA1, DHFR, ASGR2, ITGA1,
Protein Size: 291

Molekulargewicht: 33 kDa

Gen-ID: 432

NCBI Accession: NM_001671, NP_001662

UniProt: Q6FGQ5

Pathways: Thyroid Hormone Synthesis