Asialoglycoprotein Receptor 2 Antikörper (N-Term)

Produktnummer ABIN2778141

Produktdetails anti-Asialoglycoprotein Receptor 2 Antikörper

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Schwein, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Asialoglycoprotein Receptor 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LVVICVTGSQ SEGHRGAQLQ AELRSLKEAF SNFSSSTLTE VQAISTHGGS

Homologie: Human: 100%, Pig: 77%, Rat: 79%, Yeast: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against ASGR2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 311 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Asialoglycoprotein Receptor 2 Antikörper (ABIN2778141)

Chang, Lai, Chien, Liang, Adak, Chuang, Chen, Lin: "Synthesis and evaluation of a photoactive probe with a multivalent carbohydrate for capturing carbohydrate-lectin interactions." in: Bioconjugate chemistry, Vol. 24, Issue 11, pp. 1895-906, (2013) (PubMed).

Details zu Asialoglycoprotein Receptor 2

Target: Asialoglycoprotein Receptor 2 (ASGR2)

Andere Bezeichnung: ASGR2 (ASGR2 Produkte)

Synonyme: ASGR2 antikoerper, asgr2 antikoerper, MGC137129 antikoerper, ASGP-R2 antikoerper, ASGPR2 antikoerper, CLEC4H2 antikoerper, HBXBP antikoerper, HL-2 antikoerper, Asgr antikoerper, Asgr-2 antikoerper, asialoglycoprotein receptor 2 antikoerper, C-type lectin domain family 10 member A antikoerper, ASGR2 antikoerper, clec10a antikoerper, Asgr2 antikoerper, LOC100347178 antikoerper

Hintergrund: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2
Protein Interaction Partner: HDAC3, UBC, CDK6, CDK4, COPS5, TADA3, CDKN2A,
Protein Size: 311

Molekulargewicht: 35 kDa

Gen-ID: 433

NCBI Accession: NM_001181, NP_001172

UniProt: P07307

Pathways: Thyroid Hormone Synthesis