PLP1 Antikörper (Middle Region)

Produktnummer ABIN2778152

Produktdetails anti-PLP1 Antikörper

Target: PLP1 (Proteolipid Protein 1 (PLP1))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IYGTASFFFL YGALLLAEGF YTTGAVRQIF GDYKTTICGK GLSATVTGGQ

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PLP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PLP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 277 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PLP1

Target: PLP1 (Proteolipid Protein 1 (PLP1))

Andere Bezeichnung: PLP1 (PLP1 Produkte)

Synonyme: GPM6C antikoerper, HLD1 antikoerper, MMPL antikoerper, PLP antikoerper, PLP/DM20 antikoerper, PMD antikoerper, SPG2 antikoerper, Plp antikoerper, PLP1 antikoerper, plp1 antikoerper, DKFZp459O081 antikoerper, DKFZp459O113 antikoerper, DM20 antikoerper, jimpy antikoerper, jp antikoerper, msd antikoerper, rsh antikoerper, plp antikoerper, hld1 antikoerper, mmpl antikoerper, plp1a antikoerper, pmd antikoerper, spg2 antikoerper, DMalpha2c antikoerper, wu:fc27f01 antikoerper, wu:fj36d03 antikoerper, wu:fj42d08 antikoerper, zgc:110499 antikoerper, PLP-B antikoerper, plp1-a antikoerper, plp1-b antikoerper, plp1b antikoerper, proteolipid protein 1 antikoerper, proteolipid protein (myelin) 1 antikoerper, myelin proteolipid protein antikoerper, proteolipid protein 1 L homeolog antikoerper, proteolipid protein 1a antikoerper, proteolipid protein 1 S homeolog antikoerper, PLP1 antikoerper, Plp1 antikoerper, plp1 antikoerper, Tsp_11640 antikoerper, plp antikoerper, plp1.L antikoerper, plp1a antikoerper, plp1.S antikoerper

Hintergrund: PLP1 is a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2.This gene encodes a transmembrane proteolipid protein that is the predominant myelin protein present in the central nervous system. It may play a role in the compaction, stabilization, and maintenance of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in this gene cause X-linked Pelizaeus-Merzbacher disease and spastic paraplegia type 2. Alternatively spliced transcript variants encoding distinct isoforms or having different 5' UTRs, have been identified for this gene.
Alias Symbols: MMPL, PLP, PLP/DM20, PMD, SPG2, HLD1
Protein Interaction Partner: PTPRN, CLN8, Htt, ITGAV, ITGA5, MAG, MBP, CANX, CALR,
Protein Size: 277

Molekulargewicht: 30 kDa

Gen-ID: 5354

NCBI Accession: NM_000533, NP_000524

UniProt: P60201