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Kallikrein 6 Antikörper (N-Term)

KLK6 Reaktivität: Human, Hund, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2778179
  • Target Alle Kallikrein 6 (KLK6) Antikörper anzeigen
    Kallikrein 6 (KLK6)
    Bindungsspezifität
    • 15
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 39
    • 18
    • 10
    • 2
    Human, Hund, Pferd
    Wirt
    • 57
    • 5
    • 2
    Kaninchen
    Klonalität
    • 59
    • 5
    Polyklonal
    Konjugat
    • 28
    • 10
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Kallikrein 6 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 22
    • 20
    • 13
    • 13
    • 10
    • 8
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    KHNLRQRESS QEQSSVVRAV IHPDYDAASH DQDIMLLRLA RPAKLSELIQ
    Homologie
    Dog: 92%, Horse: 92%, Human: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against KLK6. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human KLK6
    Top Product
    Discover our top product KLK6 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 244 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Kallikrein 6 (KLK6)
    Andere Bezeichnung
    KLK6 (KLK6 Produkte)
    Synonyme
    Bssp antikoerper, Klk7 antikoerper, PRSS18 antikoerper, PRSS9 antikoerper, SP59 antikoerper, hK6 antikoerper, Prss9 antikoerper, AI849898 antikoerper, BSP antikoerper, Klk29 antikoerper, MSP antikoerper, Prss18 antikoerper, neurosin antikoerper, kallikrein related peptidase 6 antikoerper, kallikrein related-peptidase 6 antikoerper, kallikrein-6 antikoerper, KLK6 antikoerper, Klk6 antikoerper, LOC100716801 antikoerper
    Hintergrund
    Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The gene that encodes KLK6 protein is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. KLK6 is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.
    Alias Symbols: Bssp, Klk7, MGC9355, NEUROSIN, PRSS18, PRSS9, SP59, ZYME, hK6
    Protein Interaction Partner: SNCA, SERPINF2, SERPINC1,
    Protein Size: 244
    Molekulargewicht
    25 kDa
    Gen-ID
    5653
    NCBI Accession
    NM_001012964, NP_001012982
    UniProt
    Q92876
    Pathways
    Komplementsystem, Regulation of G-Protein Coupled Receptor Protein Signaling
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