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KIF2A Antikörper (N-Term)

KIF2A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2778183
  • Target Alle KIF2A Antikörper anzeigen
    KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 32
    • 25
    • 24
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen
    Wirt
    • 45
    • 2
    Kaninchen
    Klonalität
    • 45
    • 2
    Polyklonal
    Konjugat
    • 20
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KIF2A Antikörper ist unkonjugiert
    Applikation
    • 17
    • 15
    • 13
    • 13
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    IEPSPETPPP PASSAKVNKI VKNRRTVASI KNDPPSRDNR VVGSARARPS
    Homologie
    Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against KIF2A. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human KIF2A
    Top Product
    Discover our top product KIF2A Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 706 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KIF2A (Kinesin Heavy Chain Member 2A (KIF2A))
    Andere Bezeichnung
    KIF2A (KIF2A Produkte)
    Synonyme
    HK2 antikoerper, KIF2 antikoerper, C530030B14Rik antikoerper, Kif2 antikoerper, Kns2 antikoerper, M-kinesin antikoerper, kif2-a antikoerper, fj55b02 antikoerper, wu:fj55b02 antikoerper, kinesin family member 2A antikoerper, kinesin heavy chain member 2A L homeolog antikoerper, kinesin heavy chain member 2A antikoerper, zgc:103670 antikoerper, Kinesin-2 antikoerper, KIF2A antikoerper, Kif2a antikoerper, kif2a.L antikoerper, zgc:103670 antikoerper, GL50803_17333 antikoerper, GL50803_16456 antikoerper
    Hintergrund
    KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily. It contains 1 kinesin-motor domain. KIF2A plus end-directed microtubule-dependent motor required for normal brain development. It may regulate microtubule dynamics during axonal growth. KIF2A is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerization activity. Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles. Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM].
    Alias Symbols: HK2, KIF2
    Protein Interaction Partner: FAM13C, MRPL53, LARP1B, KIF2A, UBC, WWOX, STK4, HIST3H3, NOTCH1, HDGF, KLC2, CLSTN1, KLC1,
    Protein Size: 706
    Molekulargewicht
    80 kDa
    Gen-ID
    3796
    NCBI Accession
    NM_004520, NP_004511
    UniProt
    O00139
    Pathways
    Microtubule Dynamics, Ribonucleoprotein Complex Subunit Organization
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