KIF3B Antikörper (C-Term)

Produktnummer ABIN2778187

Produktdetails anti-KIF3B Antikörper

Target: KIF3B (Kinesin Family Member 3B (KIF3B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Hund, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIF3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: APKVQAALDA ALQDEDEIQV DASSFESTAN KKSKARPKSG RKSGSSSSSS

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against KIF3B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human KIF3B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 747 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-KIF3B Antikörper (ABIN2778187)

Weisschuh, Alavi, Bonin, Wissinger: "Identification of genes that are linked with optineurin expression using a combined RNAi--microarray approach." in: Experimental eye research, Vol. 85, Issue 4, pp. 450-61, (2007) (PubMed).

Details zu KIF3B

Target: KIF3B (Kinesin Family Member 3B (KIF3B))

Andere Bezeichnung: KIF3B (KIF3B Produkte)

Synonyme: FLA8 antikoerper, HH0048 antikoerper, KLP-11 antikoerper, AI854312 antikoerper, AW549267 antikoerper, mKIAA0359 antikoerper, kinesin family member 3B antikoerper, KIF3B antikoerper, Kif3b antikoerper

Hintergrund: The protein encoded by the KIF3B gene acts as a heterodimer with kinesin family member 3A to aid in chromosome movement during mitosis and meiosis. The encoded protein is a plus end-directed microtubule motor and can interact with the SMC3 subunit of the cohesin complex. In addition, the encoded protein may be involved in the intracellular movement of membranous organelles. This protein and kinesin family member 3A form the kinesin II subfamily of the kinesin superfamily.
Alias Symbols: PARP, PPOL, ADPRT, ADPRT1, PARP-1, ADPRT 1, pADPRT-1, KIF3B
Protein Interaction Partner: PARP1, CASP7, CASP3, UBE2I, TP53, SUMO2, CHFR, BANP, HUWE1, MDM2, SUMO3, DNMT1, CHD1L, IVNS1ABP, DDB2, PARP9, UBC, Rnf146, APLF, UHRF1, RPA3, RPA2, RPA1, ERG, MAFF, POLG2, RPL35, RPL27A, RPL19, RAD23A, PHB, CETN2, CETN1, DDX39A, PDLIM7, RPL14, MAFK, MAFG,
Protein Size: 747

Molekulargewicht: 85 kDa

Gen-ID: 142

NCBI Accession: NM_004798, NP_004789

UniProt: O15066

Pathways: Hedgehog Signalweg, M Phase