TRP63 Antikörper (Middle Region)

Produktnummer ABIN2778222

Produktdetails anti-TRP63 Antikörper

Target: TRP63 (Transformation Related Protein 63 (TRP63))

Bindungsspezifität: Middle Region

Reaktivität: Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Maus, Kaninchen, Ratte, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRP63 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VTLETRDGQV LGRRCFEARI CACPGRDRKA DEDSIRKQQV SDSAKNGDGT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against Trp63. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 461 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRP63

Target: TRP63 (Transformation Related Protein 63 (TRP63))

Andere Bezeichnung: Trp63 (TRP63 Produkte)

Synonyme: AI462811 antikoerper, Ket antikoerper, P51/P63 antikoerper, P63 antikoerper, P73l antikoerper, Tp63 antikoerper, Trp53rp1 antikoerper, transformation related protein 63 antikoerper, Trp63 antikoerper

Hintergrund: This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development. The family members include tumor proteins p53, p63, and p73, which have high sequence similarity to one another. This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis. The family members can interact with each other in many ways, including direct and indirect protein interactions. This results in mutual regulation of target gene promoters. Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium.
Alias Symbols: AI462811, Ket, MGC115972, P51/P63, P63, P73l, Tp63, Trp53rp1
Protein Interaction Partner: Trp53, Dlx6, Dlx5, Abbp1, Trp73, Perp,
Protein Size: 461

Molekulargewicht: 50 kDa

Gen-ID: 22061

NCBI Accession: NM_001114978, NP_001108450

UniProt: Q9H3D4