CCRL2 Antikörper (N-Term)

Produktnummer ABIN404914

Produktdetails anti-CCRL2 Antikörper

Target: CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCRL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LSAQLVPSLC SAVFVIGVLD NLLVVLILVK YKGLKRVENI YLLNLAVSNL

Homologie: Cow: 77%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 90%, Rat: 82%

Produktmerkmale: This is a rabbit polyclonal antibody against CCRL2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CCRL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 344 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CCRL2

Target: CCRL2 (Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))

Andere Bezeichnung: CCRL2 (CCRL2 Produkte)

Synonyme: CCRL2 antikoerper, ACKR5 antikoerper, CKRX antikoerper, CRAM antikoerper, CRAM-A antikoerper, CRAM-B antikoerper, HCR antikoerper, 1810047I05Rik antikoerper, Ackr5 antikoerper, CCR11 antikoerper, Cmkbr1l2 antikoerper, E01 antikoerper, L-CCR antikoerper, C-C motif chemokine receptor like 2 antikoerper, chemokine (C-C motif) receptor-like 2 antikoerper, Ccrl2 antikoerper, CCRL2 antikoerper

Hintergrund: CCRL2 is a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. CCRL2 gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located.
Alias Symbols: CKRX, CRAM-A, CRAM-B, HCR, MGC116710, CRAM
Protein Size: 344

Molekulargewicht: 39 kDa

Gen-ID: 9034

NCBI Accession: NM_003965, NP_003956

UniProt: O00421