SUPT5H Antikörper (Middle Region)

Produktnummer ABIN2778245

Produktdetails anti-SUPT5H Antikörper

Target: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Hund, Rind (Kuh), Ratte, Kaninchen, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUPT5H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FEDQPEGIDL EVVTESTGKE REHNFQPGDN VEVCEGELIN LQGKILSVDG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SUPT5H. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SUPT5H

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1087 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SUPT5H Antikörper (ABIN2778245)

Ueki, Lin, Senoo, Ebihara, Agata, Onji, Saheki, Kawai, Mukherjee, Reichenberger, Olsen: "Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice." in: Cell, Vol. 128, Issue 1, pp. 71-83, (2007) (PubMed).

Amir-Zilberstein, Ainbinder, Toube, Yamaguchi, Handa, Dikstein: "Differential regulation of NF-kappaB by elongation factors is determined by core promoter type." in: Molecular and cellular biology, Vol. 27, Issue 14, pp. 5246-59, (2007) (PubMed).

Details zu SUPT5H

Target: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Andere Bezeichnung: SUPT5H (SUPT5H Produkte)

Synonyme: SPT5 antikoerper, SPT5H antikoerper, Tat-CT1 antikoerper, F13P17.5 antikoerper, F13P17_5 antikoerper, Spt5 antikoerper, etID10129.15 antikoerper, etID37101.15 antikoerper, fb37g01 antikoerper, fb95e05 antikoerper, fog antikoerper, foggy antikoerper, wu:fb37g01 antikoerper, wu:fb95e05 antikoerper, wu:fc10f02 antikoerper, spt5 antikoerper, spt5h antikoerper, tat-ct1 antikoerper, CG7626 antikoerper, DSIF antikoerper, Dmel\\CG7626 antikoerper, Dspt5 antikoerper, dDSIF antikoerper, dSpt5 antikoerper, CaO19.1453 antikoerper, SPT5 homolog, DSIF elongation factor subunit antikoerper, transcription elongation factor SPT5 antikoerper, Transcription elongation factor Spt5 antikoerper, transcription elongation factor Spt5 antikoerper, transcription elongation factor spt5 antikoerper, hypothetical protein antikoerper, SPT5 homolog, DSIF elongation factor subunit S homeolog antikoerper, CG7626 gene product from transcript CG7626-RA antikoerper, Transcription elongation factor SPT5 antikoerper, transcription elongation factor antikoerper, SUPT5H antikoerper, LOC413814 antikoerper, AT2G34210 antikoerper, spt5 antikoerper, MGYG_08422 antikoerper, TERG_05483 antikoerper, PGTG_18458 antikoerper, supt5h antikoerper, Supt5h antikoerper, supt5h.S antikoerper, Spt5 antikoerper, spt-5 antikoerper, SPT5 antikoerper

Hintergrund: SUPT5H and its binding partner regulate transcriptional elongation by RNA polymerase II. SPT4 and SPT5 are involved in both 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB)-mediated transcriptional inhibition and the activation of transcriptional elongation by the human immunodeficiency virus type 1 (HIV-1) Tat protein.
Alias Symbols: FLJ34157, SPT5, SPT5H, Tat-CT1
Protein Interaction Partner: POLR2A, BRCA1, UBC, RNF2, SAMHD1, GANAB, SWAP70, PAICS, CARM1, FARSB, SEC24C, RANBP3, CSDE1, SF1, SET, PLOD2, MSH2, MSH6, GART, XRCC6, ATP6V1B2, SOX2, LMNA, CDK9, CCNT2, CCNT1, tat, NSMF, FN1, CSNK2A1, SIK1, ZNF512B, LMAN2, ZFYVE9, SNX4, SUPT4H1, POLR2C,
Protein Size: 1087

Molekulargewicht: 121 kDa

Gen-ID: 6829

NCBI Accession: NM_003169, NP_003160

UniProt: O00267