PPARA Antikörper (C-Term)

Produktnummer ABIN2778248

Produktdetails anti-PPARA Antikörper

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Schwein, Meerschweinchen, Ziege, Kaninchen, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPARA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LHLQSNHPDD TFLFPKLLQK MVDLRQLVTE HAQLVQVIKK TESDAALHPL

Homologie: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%, Sheep: 77%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against Ppara. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 468 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PPARA Antikörper (ABIN2778248)

Gu, Yang, Lin, Li, Li, Zhong, Peng, Cui: "Genetic ablation of solute carrier family 7a3a leads to hepatic steatosis in zebrafish during fasting." in: Hepatology (Baltimore, Md.), Vol. 60, Issue 6, pp. 1929-41, (2014) (PubMed).

Details zu PPARA

Target: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Andere Bezeichnung: Ppara (PPARA Produkte)

Synonyme: NR1C1 antikoerper, PPAR antikoerper, PPARalpha antikoerper, hPPAR antikoerper, LOC100136415 antikoerper, PPARALPHA antikoerper, nr1c1 antikoerper, xPPARalpha antikoerper, xppara antikoerper, 4933429D07Rik antikoerper, AW742785 antikoerper, Nr1c1 antikoerper, PPAR-alpha antikoerper, Ppar antikoerper, peroxisome proliferator activated receptor alpha antikoerper, peroxisome proliferator-activated receptor alpha antikoerper, peroxisome proliferator activated receptor alpha L homeolog antikoerper, PPARA antikoerper, LOC100136415 antikoerper, ppara.L antikoerper, Ppara antikoerper, ppara antikoerper

Hintergrund: As a nuclear steroid receptor, Ppara heterodimerizes with retinoid-X receptor (RXR), and binds to peroxisome proliferator response elements (PPREs) to initiate the transcriptional regulation of target genes.
Alias Symbols: PPAR
Protein Interaction Partner: HSP90AA1, Mdm2, Ubc, NRIP1, Dut,
Protein Size: 468

Molekulargewicht: 51 kDa

Gen-ID: 25747

NCBI Accession: NM_013196, NP_037328

UniProt: P37230

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C