Membralin Antikörper (Middle Region)

Produktnummer ABIN2778282

Produktdetails anti-Membralin Antikörper

Target: Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

Bindungsspezifität: Middle Region

Reaktivität: Zebrafisch (Danio rerio), Human, Meerschweinchen, Ratte, Hund, Maus, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Membralin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: YDDILMSSVK GLAENEENKG FLRNVVSGEH YRFVSMWMAR TSYLAAFAIM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against C19ORF6. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human C19ORF6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 408 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Membralin

Target: Membralin (TMEM259) (Transmembrane Protein 259 (TMEM259))

Andere Bezeichnung: C19ORF6 (TMEM259 Produkte)

Synonyme: ASBABP1 antikoerper, C19orf6 antikoerper, MBRL antikoerper, MEMBRALIN antikoerper, R32184_3 antikoerper, C28H19orf6 antikoerper, c19orf6 antikoerper, AC087114.7gm12 antikoerper, AC087114.7gm2 antikoerper, ORF61 antikoerper, mFLJ00277 antikoerper, Mbrl antikoerper, RGD1311136 antikoerper, transmembrane protein 259 antikoerper, transmembrane protein 259 L homeolog antikoerper, TMEM259 antikoerper, tmem259.L antikoerper, Tmem259 antikoerper

Hintergrund: Human membralin is unique and does not share significant sequence homology with other human genes, only membralins of other species. The membralin gene contains 11 exons which encode at least two spliced variants in human cancer. The long form of membralin (membralin-1) comprises all 11 exons, encoding a protein of 620-amino acids long and the short form of membralin (membralin-3) contains all exons except for exon 10, encoding a protein of 408 amino acids. Expression of different membralin isoforms depends on tissue type. The long form, membralin-1, is expressed in ovarian and colorectal carcinomas but not in breast or pancreatic carcinomas, which express only the short splice form, membralin-3. Recent studies suggest that membralin is a novel tumor-associated marker in ovarian serous carcinomas
Alias Symbols: MBRL, ASBABP1, R32184_3, MEMBRALIN, C19ORF6
Protein Interaction Partner: ADRB2, UBC, TMEM173, ARSE,
Protein Size: 408

Molekulargewicht: 46 kDa

Gen-ID: 91304

NCBI Accession: NM_033420, NP_219488