MED17 Antikörper (N-Term)
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- Target Alle MED17 Antikörper anzeigen
- MED17 (Mediator Complex Subunit 17 (MED17))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MED17 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)
- Sequenz
- AAQILLKGAE RLTKSVTENQ ENKLQRDFNS ELLRLRQHWK LRKVGDKILG
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CRSP6. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CRSP6
- Top Product
- Discover our top product MED17 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 651 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MED17 (Mediator Complex Subunit 17 (MED17))
- Andere Bezeichnung
- CRSP6 (MED17 Produkte)
- Synonyme
- crsp6 antikoerper, CRSP6 antikoerper, CRSP77 antikoerper, DRIP80 antikoerper, TRAP80 antikoerper, 77kDa antikoerper, C330002H14Rik antikoerper, Crsp6 antikoerper, Trap80 antikoerper, mediator of RNA polymerase II transcription subunit 17 antikoerper, mediator complex subunit 17 antikoerper, mediator complex subunit 17 L homeolog antikoerper, AOR_1_2446154 antikoerper, VDBG_01663 antikoerper, med17 antikoerper, med17.L antikoerper, MED17 antikoerper, Med17 antikoerper
- Hintergrund
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
Alias Symbols: CRSP6, CRSP77, DRIP80, TRAP80
Protein Interaction Partner: UBC, BRCA1, CDK19, CDK8, MED26, POLR2C, ESR2, MED19, FBXW7, EPAS1, TFIP11, MED24, MED21, MED14, MED11, MED28, WDR33, CPSF2, UBD, BCL6, SMARCA4, SUZ12, MED10, CTDP1, SREBF1, MED25, MED15, TRA, MED1, OBFC1, MED18, ZC3H13, MED12, QKI, TRIP4, TADA2A, SUPT7L,
Protein Size: 651 - Molekulargewicht
- 73 kDa
- Gen-ID
- 9440
- NCBI Accession
- NM_004268, NP_004259
- UniProt
- Q9NVC6
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
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