ASH2L Antikörper (Middle Region)

Produktnummer ABIN2778325

Produktdetails anti-ASH2L Antikörper

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASH2L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: AAGSSGKGRG AKRKQQDGGT TGTTKKARSD PLFSAQRLPP HGYPLEHPFN

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ASH2L. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASH2L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 628 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ASH2L

Target: ASH2L (Set1/Ash2 Histone Methyltransferase Complex Subunit ASH2 (ASH2L))

Andere Bezeichnung: ASH2L (ASH2L Produkte)

Synonyme: ASH2 antikoerper, ASH2L1 antikoerper, ASH2L2 antikoerper, Bre2 antikoerper, fb34c06 antikoerper, fe38b04 antikoerper, fi20h02 antikoerper, wu:fb34c06 antikoerper, wu:fe38b04 antikoerper, wu:fi20h02 antikoerper, zgc:171444 antikoerper, ASH2L antikoerper, ash2-like antikoerper, ASH2 like histone lysine methyltransferase complex subunit antikoerper, ash2 (absent, small, or homeotic)-like (Drosophila) antikoerper, ash2 (absent, small, or homeotic)-like L homeolog antikoerper, ASH2L antikoerper, Ash2l antikoerper, ash2l antikoerper, ash2l.L antikoerper

Hintergrund: ASH2L is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. The protein may function as a transcriptional regulator and play a role in hematopoiesis.
Alias Symbols: ASH2, ASH2L1, ASH2L2, Bre2
Protein Interaction Partner: CXXC1, DPY30, SETD1A, RBBP5, PPARG, KMT2A, KMT2D, UBC, SENP3, KDM6A, PPP1CC, SMAD9, KDM6B, WWP1, BRCA1, BARD1, WDR5, MEN1, USF1, KMT2C, HCFC2, SETD1B, KDM4B, KMT2B, HCFC1, ESR1, CDC73, HIST3H3, PYGO2, WDR82, PSMC5, PRMT1, E2F4, E2F1, PAGR1, NCOA6, PAXIP1,
Protein Size: 628

Molekulargewicht: 69 kDa

Gen-ID: 9070

NCBI Accession: NM_004674, NP_004665

UniProt: Q9UBL3