RBBP5 Antikörper (Middle Region)

Produktnummer ABIN2778328

Produktdetails anti-RBBP5 Antikörper

Target: RBBP5 (Retinoblastoma Binding Protein 5 (RBBP5))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBBP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GASSEKKRQS SADGSQPPKK KPKTTNIELQ GVPNDEVHPL LGVKGDGKSK

Homologie: Cow: 100%, Dog: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RBBP5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RBBP5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 538 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RBBP5

Target: RBBP5 (Retinoblastoma Binding Protein 5 (RBBP5))

Andere Bezeichnung: RBBP5 (RBBP5 Produkte)

Synonyme: MGC56078 antikoerper, zgc:56078 antikoerper, zgc:85864 antikoerper, rbbp5 antikoerper, MGC80141 antikoerper, RBBP5 antikoerper, MGC97793 antikoerper, DKFZp469C191 antikoerper, RBQ3 antikoerper, SWD1 antikoerper, 4933411J24Rik antikoerper, C330016J05 antikoerper, RB binding protein 5, histone lysine methyltransferase complex subunit antikoerper, retinoblastoma binding protein 5 antikoerper, retinoblastoma binding protein 5 S homeolog antikoerper, retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit antikoerper, RBBP5 antikoerper, rbbp5 antikoerper, rbbp5.S antikoerper, Rbbp5 antikoerper

Hintergrund: RBBP5 contains 6 WD repeats. It binds preferentially to underphosphorylated retinoblastoma protein. The protein encoded by this gene is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-1 AU099032.1 13-13 2-26 CD710496.1 39-63 27-567 BC053856.1 17-557 568-1604 BC037284.2 540-1576 1605-2978 BC053856.1 1595-2968 2979-2979 BC037284.2 2838-2838 2980-2992 AA235403.1 1-13 2993-3136 BC037284.2 2851-2994 3137-3318 BC053856.1 3125-3306 3319-3334 BC037284.2 3177-3192 3335-3342 BG392257.1 177-184 3343-3587 BC037284.2 3200-3444 3588-3683 CB133829.1 341-436
Alias Symbols: RBQ3, SWD1
Protein Interaction Partner: CXXC1, SETD1A, ASH2L, PPARG, KMT2A, KMT2D, SENP3, UBE2I, UBC, SUMO2, Fbxl16, KDM6B, KDM6A, SMARCD1, KLC2, SRRT, DHX38, SMARCE1, SMARCD2, HCFC1, SMARCC1, MEN1, USF1, WDR5, ELAVL1, ESR1, KANSL1, DPY30, KDM4B, KMT2B, PSMA3, CTBP1, TBK1, CDC73, HIST3H3, PYGO2
Protein Size: 538

Molekulargewicht: 59 kDa

Gen-ID: 5929

NCBI Accession: NM_005057, NP_005048

UniProt: Q15291