Afadin Antikörper (N-Term)

Produktnummer ABIN2778340

Produktdetails anti-Afadin Antikörper

Target: Afadin (MLLT4)

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schwein, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Afadin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GVIQNFKRTL SKKEKKEKKK REKEALRQAS DKDDRPFQGE DVENSRLAAE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 85%, Rat: 100%, Yeast: 92%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against MLLT4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MLLT4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 674 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Afadin

Target: Afadin (MLLT4)

Andere Bezeichnung: MLLT4 (MLLT4 Produkte)

Synonyme: MLLT4 antikoerper, af-6 antikoerper, af6 antikoerper, si:ch211-278j12.1 antikoerper, AF6 antikoerper, RP3-431P23.3 antikoerper, 5033403D15Rik antikoerper, Af-6 antikoerper, Afadin antikoerper, Gm314 antikoerper, I-afadin antikoerper, S-afadin antikoerper, Af6 antikoerper, afadin, adherens junction formation factor antikoerper, afadin, adherens junction formation factor L homeolog antikoerper, afadin, adherens junction formation factor a antikoerper, afadin antikoerper, AFDN antikoerper, afdn.L antikoerper, afdna antikoerper, LOC589923 antikoerper, LOC100177180 antikoerper, afdn antikoerper, Afdn antikoerper

Hintergrund: AF6 is a Ras target that regulates cell-cell adhesions downstream of Ras activation. It is fused with MLL in leukemias caused by t(6,11) translocations.
Alias Symbols: RP3-470B24.4, AF-6, AF6, AFADIN, FLJ34371, RP3-431P23.3
Protein Interaction Partner: UBC, LGR4, LATS2, YWHAQ, YWHAE, VCAM1, SMAD2, ITGA4, GRB2, FN1, SIRT7, HNRNPA1, ARRB2, YWHAG, YWHAB, KMT2A, MEN1, PVRL4, PICK1, RIT2, SORBS2, F11R, NRXN2, SSX2IP, RIT1, NRXN3, PVRL3, PVRL1, MRAS, SORBS1, EPHB6, EPHA7, JAG1, EPHB3, RALGDS, TJP1, EPHB2, PVR
Protein Size: 674

Molekulargewicht: 74 kDa

Gen-ID: 4301

NCBI Accession: NM_001040000

UniProt: P55196

Pathways: Cell-Cell Junction Organization