AFF3 Antikörper (Middle Region)

Produktnummer ABIN2778345

Produktdetails anti-AFF3 Antikörper

Target: AFF3 (AF4/FMR2 Family, Member 3 (AFF3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Schwein, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: APATKDSESA PPSHTSDTPA EKALPKSKRK RKCDNEDDYR EIKKSQGEKD

Homologie: Dog: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 77%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against AFF3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AFF3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1226 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-AFF3 Antikörper (ABIN2778345)

To, Faseruk, Gokgoz, Pinnaduwage, Done, Andrulis: "LAF-4 is aberrantly expressed in human breast cancer." in: International journal of cancer. Journal international du cancer, Vol. 115, Issue 4, pp. 568-74, (2005) (PubMed).

Details zu AFF3

Target: AFF3 (AF4/FMR2 Family, Member 3 (AFF3))

Andere Bezeichnung: AFF3 (AFF3 Produkte)

Synonyme: id:ibd5053 antikoerper, LAF4 antikoerper, MLLT2-like antikoerper, 3222402O04Rik antikoerper, A730046J16 antikoerper, LAF-4 antikoerper, Laf4 antikoerper, AF4/FMR2 family member 3 antikoerper, AF4/FMR2 family, member 3 antikoerper, AFF3 antikoerper, aff3 antikoerper, Aff3 antikoerper

Hintergrund: AFF3 is a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL.This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Alias Symbols: LAF4, MLLT2-like
Protein Interaction Partner: CDK9, MLLT3,
Protein Size: 1226

Molekulargewicht: 133 kDa

Gen-ID: 3899

NCBI Accession: NM_002285, NP_002276

UniProt: P51826