TRIM8 Antikörper (N-Term)

Produktnummer ABIN2778368

Produktdetails anti-TRIM8 Antikörper

Target: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Schwein, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RGCIGEAWAK DSGLVRCPEC NQAYNQKPGL EKNLKLTNIV EKFNALHVEK

Homologie: Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TRIM8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 551 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TRIM8

Target: TRIM8 (Tripartite Motif Containing 8 (TRIM8))

Andere Bezeichnung: TRIM8 (TRIM8 Produkte)

Synonyme: GERP antikoerper, RNF27 antikoerper, AA408830 antikoerper, BB006755 antikoerper, Rnf27 antikoerper, si:ch211-208d15.5 antikoerper, wu:fc90g07 antikoerper, tripartite motif containing 8 antikoerper, tripartite motif containing 8 L homeolog antikoerper, tripartite motif-containing 8 antikoerper, tripartite motif containing 8b antikoerper, TRIM8 antikoerper, trim8.L antikoerper, Trim8 antikoerper, trim8b antikoerper

Hintergrund: TRIM8 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes.
Alias Symbols: GERP, RNF27
Protein Interaction Partner: BRAP, TRIM25, PCGF5, MSL2, RNF141, TRIM2, USP7, TP53, CCNH, OTUB2, USP21, USP39, USP2, TNFAIP3, UBE2D2, TRIM47, TRIM15, TRIM8, RAD18, TRIM39, RNF111, RC3H2, RNF138, RNF181, RCHY1, RNF41, TRIM43, UHRF2, TRIM9, RNF7, TRIM24, RNF113A, MKRN3, TRAF5, TRIM21, S
Protein Size: 551

Molekulargewicht: 61 kDa

Gen-ID: 81603

NCBI Accession: NM_030912, NP_112174

UniProt: Q9BZR9