ZNF496 Antikörper (N-Term)

Produktnummer ABIN2778404

Produktdetails anti-ZNF496 Antikörper

Target: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Bindungsspezifität: N-Term

Reaktivität: Maus, Human, Ratte, Rind (Kuh), Schaf, Hund, Pferd, Schwein, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF496 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MPTALCPRVL APKESEEPRK MRSPPGENPS PQGELPSPES SRRLFRRFRY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ZNF496. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF496

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 587 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ZNF496

Target: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Andere Bezeichnung: ZNF496 (ZNF496 Produkte)

Hintergrund: ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.
Alias Symbols: NIZP1, ZFP496, ZKSCAN17
Protein Interaction Partner: ZKSCAN4, ZSCAN22, ZNF483, ZNF446, ZSCAN12, ZSCAN21, ARR3, Nsd1, SUMO2, UBC, CBX3, TRIM28, NR3C1, POLR3D, ZZZ3, JADE2, RAI1, SSX3, SUPT5H, PPARG,
Protein Size: 587

Molekulargewicht: 67 kDa

Gen-ID: 84838

NCBI Accession: NM_032752, NP_116141

UniProt: Q96IT1