HOXA9 Antikörper (Middle Region)

Produktnummer ABIN405287

Produktdetails anti-HOXA9 Antikörper

Target: HOXA9 (Homeobox A9 (HOXA9))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HOXA9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KEFLFNMYLT RDRRYEVARL LNLTERQVKI WFQNRRMKMK KINKDRAKDE

Homologie: Cow: 85%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 85%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HOXA9. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human HOXA9

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 272 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HOXA9 Antikörper (ABIN405287)

Wang, Zeng, Chen, Ding, Zhong, Zhao, Wang, Sarver, Koller, Zhi, Ma, Yu, Chen, Huang: "BRCA1 is a negative modulator of the PRC2 complex." in: The EMBO journal, Vol. 32, Issue 11, pp. 1584-97, (2013) (PubMed).

Details zu HOXA9

Target: HOXA9 (Homeobox A9 (HOXA9))

Andere Bezeichnung: HOXA9 (HOXA9 Produkte)

Hintergrund: In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA9 gene is part of the A cluster on chromosome 7 and the protein is a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ABD-B, HOX1, HOX1.7, HOX1G, MGC1934
Protein Interaction Partner: TRIP6, PRMT5, CUL4A, UBC, CREBBP, PBX3, RBPMS, PBX2, PBX1, PLSCR1, MEIS2, MEIS1, SMAD2, SMAD4, JUN, NFKBIA, BCR, KMT2A,
Protein Size: 272

Molekulargewicht: 30 kDa

Gen-ID: 3205

NCBI Accession: NM_152739, NP_689952

UniProt: P31269