PHAP1 Antikörper (N-Term)

Produktnummer ABIN2778668

Produktdetails anti-PHAP1 Antikörper

Target: PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Kaninchen, Schaf, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MEMGRRIHLE LRNRTPSDVK ELVLDNSRSN EGKLEGLTDE FEELEFLSTI

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 86%, Sheep: 77%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ANP32A. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANP32A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 249 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PHAP1

Target: PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))

Andere Bezeichnung: ANP32A (ANP32A Produkte)

Hintergrund: ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.
Alias Symbols: LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1
Protein Interaction Partner: UBC, rev, PDLIM5, PLIN3, ARPC1B, OXSR1, EIF4A3, VBP1, TPD52L2, SSB, SRP14, RPA2, PKM, BAG1, SOX2, PCBP1, ESR1, THRB, PPARG, PGR, KPNA6, KPNA5, KPNA1, SUMO2, CHAF1A, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, SET, MEPCE, ELAVL1, ADAP1, NSFL1C, HSPB3, AXIN1,
Protein Size: 249

Molekulargewicht: 29 kDa

Gen-ID: 8125

NCBI Accession: NM_006305, NP_006296

UniProt: P39687