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Cytokeratin 18 Antikörper (N-Term)

Name: Cytokeratin 18 Antikörper (N-Term)
SKU: ABIN2778669
Price: 470.22 EUR
Availability: InStock

KRT18 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated

Rabbit Anti-KRT18 Antibody Paraffin Embedded Tissue: Human Lung Cellular Data: Alveolar cells Antibody Concentration: 4. (Cytokeratin 18 Antikörper (N-Term))

IHC

WB Suggested Anti-KRT18 Antibody Titration: 1. (Cytokeratin 18 Antikörper (N-Term))

Rabbit Anti-KRT18 Antibody Paraffin Embedded Tissue: Human alveolar cell Cellular Data: Epithelial cells of renal tubule Antibody Concentration: 4. (Cytokeratin 18 Antikörper (N-Term))

IHC

WB Suggested Anti-KRT18 antibody Titration: 1 ug/mL Sample Type: Human HepG2 (Cytokeratin 18 Antikörper (N-Term))

WB Suggested Anti-KRT18 antibody Titration: 1 ug/mL Sample Type: Human Hela (Cytokeratin 18 Antikörper (N-Term))

6 Abbildungen

Produktnummer ABIN2778669

Datenblatt (PDF)

Target Alle Cytokeratin 18 (KRT18) Antikörper anzeigen

Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))
Bindungsspezifität
25

16

15

14

12

12

6

6

6

5

4

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reaktivität
243

129

94

43

34

25

23

19

19

17

16

14

14

14

8

7

7

7

4

2

2

1
Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen
Wirt
147

128

3

1

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
146

134

1
Polyklonal
Konjugat
147

23

22

10

4

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

1

1
Dieser Cytokeratin 18 Antikörper ist unkonjugiert
Applikation
220

102

87

80

70

56

54

40

39

27

27

19

8

8

7

6

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz

TRSTFSTNYR SLGSVQAPSY GARPVSSAAS VYAGAGGSGS RISVSRSTSF

Homologie

Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale

This is a rabbit polyclonal antibody against KRT18. It was validated on Western Blot and immunohistochemistry.

Aufreinigung

Protein A purified

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human KRT18

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KRT18 Reaktivität: Human WB, IF, ELISA, IHC (p), IP Wirt: Maus Monoclonal 2F8 unconjugated

Applikationshinweise

Optimal working dilutions should be determined experimentally by the investigator.

Kommentare

Antigen size: 430 AA

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

Cytokeratin 18 (KRT18) (Keratin 18 (KRT18))

Andere Bezeichnung

KRT18 (KRT18 Produkte)

Hintergrund

KRT18 (Keratin 18) is type I intermediate filament chain. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis.KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: K18, CYK18
Protein Interaction Partner: KRT18, GOLGA2, UBC, HAUS1, CCDC146, MDM2, EED, HNRNPU, FLII, FKBP3, DDX1, C14orf166, RTCB, CNOT1, SEC16A, RPL14, RFC2, UPF2, BBS7, PAN2, BBS4, BBS2, BBS1, SMARCD1, ORC5, NOS2, KRT8, KPNA2, ITGA4, HRAS, GRN, FN1, EP300, ATF2, CDH1, CDC5L, YTHDC1, PIAS4, TX
Protein Size: 430

Molekulargewicht

47 kDa

Gen-ID

3875

NCBI Accession

NM_000224, NP_000215

UniProt

P05783

Pathways

Apoptose, Caspase Kaskade in der Apoptose