RPL8 Antikörper (C-Term)

Produktnummer ABIN2778675

Produktdetails anti-RPL8 Antikörper

Target: RPL8 (Ribosomal Protein L8 (RPL8))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPL8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: KKVISSANRA VVGVVAGGGR IDKPILKAGR AYHKYKAKRN CWPRVRGVAM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RPL8. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RPL8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 257 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RPL8 Antikörper (ABIN2778675)

Wong, Traynor, Basse, Kay, Warren: "Defective ribosome assembly in Shwachman-Diamond syndrome." in: Blood, Vol. 118, Issue 16, pp. 4305-12, (2011) (PubMed).

Details zu RPL8

Target: RPL8 (Ribosomal Protein L8 (RPL8))

Andere Bezeichnung: RPL8 (RPL8 Produkte)

Synonyme: L8 antikoerper, zgc:73105 antikoerper, zgc:77641 antikoerper, CG1263 antikoerper, Dmel\\CG1263 antikoerper, M(3)62F antikoerper, M(3)LS2 antikoerper, Rp L8 antikoerper, anon-EST:Posey5 antikoerper, rpL8 antikoerper, RPL8 antikoerper, ribosomal protein L8 antikoerper, ribosomal protein L8 S homeolog antikoerper, Ribosomal protein L8 antikoerper, microRNA 6850 antikoerper, RPL8 antikoerper, Rpl8 antikoerper, rpl8.S antikoerper, rpl8 antikoerper, RpL8 antikoerper, MIR6850 antikoerper

Hintergrund: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL8 is a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm.Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L2P family of ribosomal proteins. It is located in the cytoplasm. In rat, the protein associates with the 5.8S rRNA, very likely participates in the binding of aminoacyl-tRNA, and is a constituent of the elongation factor 2-binding site at the ribosomal subunit interface. Alternatively spliced transcript variants encoding the same protein exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: L8
Protein Interaction Partner: TP53, HUWE1, SUMO2, TUBGCP3, CEP250, STAU1, UBC, MDM2, ZBTB1, EED, RPS25, RPL28, PARK2, FBXO6, UPF2, TARDBP, ICAM1, IGSF8, PAN2, ITGA4, IL7R, FN1, DPH3, UBL4A, VCAM1, EIF4A3, PA2G4, MAGOH, ESR1, RPLP0P6, RPL10L, TUBA1C, ATF7IP, RPL36, TXN2, PPT2, RPL23, R
Protein Size: 257

Molekulargewicht: 28 kDa

Gen-ID: 6132

NCBI Accession: NM_000973, NP_000964

UniProt: P62917

Pathways: Regulation of Cell Size