EXOSC10 Antikörper (C-Term)
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- Target Alle EXOSC10 Antikörper anzeigen
- EXOSC10 (Exosome Component 10 (EXOSC10))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Rind (Kuh), Kaninchen, Ratte, Hund, Meerschweinchen, Pferd, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EXOSC10 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- ACKAAAEQAI SVRQQVVLEN AAKKRERATS DPRTTEQKQE KKRLKISKKP
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against EXOSC10. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region region of human EXOSC10
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 885 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).
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Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).
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- Target
- EXOSC10 (Exosome Component 10 (EXOSC10))
- Andere Bezeichnung
- EXOSC10 (EXOSC10 Produkte)
- Hintergrund
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EXOSC10 contains 1 HRDC domain and 1 3'-5' exonuclease domain. Antibodies against PM/SCL are found in patients with polymyositis and/or scleroderma.
Alias Symbols: PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4
Protein Interaction Partner: SUMO2, UBC, SUMO1, RPA3, RPA2, RPA1, NOMO2, EXOSC6, FERMT3, CHPF, LSM2, EXOSC5, FOXRED1, EXOSC4, XRN1, LSM8, B9D1, USP21, UPF2, NOMO1, EXOSC7, DIS3, EXOSC8, IMMT, RUVBL2, EIF3M, TOX4, SSRP1, SKIV2L, LCAT, DXO, ALDH1B1, AICDA, ESR1, EXOSC3, EXOSC9, DIS3L,
Protein Size: 885 - Molekulargewicht
- 101 kDa
- Gen-ID
- 5394
- NCBI Accession
- NM_001001998, NP_001001998
- UniProt
- Q01780
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