EXOSC3 Antikörper (C-Term)

Produktnummer ABIN2778686

Produktdetails anti-EXOSC3 Antikörper

Target: EXOSC3 (Exosome Component 3 (EXOSC3))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOSC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VIGIVTAKSG DIFKVDVGGS EPASLSYLSF EGATKRNRPN VQAISSRL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 91%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EXOSC3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EXOSC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 164 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EXOSC3 Antikörper (ABIN2778686)

Fan, Huang-Liu, Shen, Ju, Lin, Pai, Huang, Ho, Tsai, Tsai, Huang: "Reduction of TLR4 mRNA stability and protein expressions through inhibiting cytoplasmic translocation of HuR transcription factor by E₂ and/or ERα in LPS-treated H9c2 cardiomyoblast cells." in: The Chinese journal of physiology, Vol. 57, Issue 1, pp. 8-18, (2014) (PubMed).

Details zu EXOSC3

Target: EXOSC3 (Exosome Component 3 (EXOSC3))

Andere Bezeichnung: EXOSC3 (EXOSC3 Produkte)

Synonyme: PCH1B antikoerper, RP11-3J10.8 antikoerper, RRP40 antikoerper, Rrp40p antikoerper, bA3J10.7 antikoerper, hRrp-40 antikoerper, p10 antikoerper, 2310005D06Rik antikoerper, AI593501 antikoerper, Rrp40 antikoerper, im:7140537 antikoerper, zgc:112345 antikoerper, exosome component 3 antikoerper, exosome component 3 L homeolog antikoerper, EXOSC3 antikoerper, exosc3.L antikoerper, Exosc3 antikoerper, exosc3 antikoerper

Hintergrund: EXOSC3 is component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5.8S rRNA.
Alias Symbols: CGI-102, MGC15120, MGC723, RP11-3J10.8, RRP40, Rrp40p, bA3J10.7, hRrp40p, p10, hRrp-40
Protein Interaction Partner: UBC, EXOSC5, EXOSC4, CDK5RAP1, EXOSC8, ATP5D, AICDA, EXOSC10, EXOSC9, APP, EXOSC2, EXOSC6, DIS3L, EXOSC1, EXOSC3, EXOSC7, DIS3, MPHOSPH6, HDGF, KHSRP,
Protein Size: 164

Molekulargewicht: 17 kDa

Gen-ID: 51010

NCBI Accession: NM_001002269, NP_001002269

UniProt: Q9NQT5

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interaktom