DAZ2 Antikörper (N-Term)

Produktnummer ABIN2778701

Produktdetails anti-DAZ2 Antikörper

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Kaninchen, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAZ2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MDETEIGSCF GRYGSVKEVK IITNRTGVSK GYGFVSFVND VDVQKIVGSQ

Homologie: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DAZ2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DAZ2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 534 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DAZ2

Target: DAZ2 (Deleted in Azoospermia 2 (DAZ2))

Andere Bezeichnung: DAZ2 (DAZ2 Produkte)

Synonyme: pDP1678 antikoerper, DAZ2 antikoerper, deleted in azoospermia 2 antikoerper, deleted in azoospermia protein 2 antikoerper, DAZ2 antikoerper, LOC738583 antikoerper

Hintergrund: DAZ2 is a member of the DAZ family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). This RNA-binding protein is important for spermatogenesis.This gene is a member of the DAZ gene family and is a candidate for the human Y-chromosomal azoospermia factor (AZF). Its expression is restricted to premeiotic germ cells, particularly in spermatogonia. It encodes an RNA-binding protein that is important for spermatogenesis. Four copies of this gene are found on chromosome Y within palindromic duplications, one pair of genes is part of the P2 palindrome and the second pair is part of the P1 palindrome. Each gene contains a 2.4 kb repeat including a 72-bp exon, called the DAZ repeat, the number of DAZ repeats is variable and there are several variations in the sequence of the DAZ repeat. Each copy of the gene also contains a 10.8 kb region that may be amplified, this region includes five exons that encode an RNA recognition motif (RRM) domain. This gene contains one copy of the 10.8 kb repeat. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: pDP1678
Protein Interaction Partner: UBC, PUM2,
Protein Size: 534

Molekulargewicht: 59 kDa

Gen-ID: 57055

NCBI Accession: NM_001005785, NP_001005785

UniProt: Q2KHN6