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U2AF2 Antikörper (N-Term)

U2AF59 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2778722
  • Target Alle U2AF2 (U2AF59) Antikörper anzeigen
    U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
    Bindungsspezifität
    • 14
    • 9
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 50
    • 23
    • 16
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen, Zebrafisch (Danio rerio)
    Wirt
    • 49
    • 1
    Kaninchen
    Klonalität
    • 48
    • 2
    Polyklonal
    Konjugat
    • 22
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser U2AF2 Antikörper ist unkonjugiert
    Applikation
    • 32
    • 18
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    EFERQLNENK QERDKENRHR KRSHSRSRSR DRKRRSRSRD RRNRDQRSAS
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against U2AF2. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Protein A purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human U2AF2
    Top Product
    Discover our top product U2AF59 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 471 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Sickmier, Frato, Kielkopf: "Crystallization and preliminary X-ray analysis of a U2AF65 variant in complex with a polypyrimidine-tract analogue by use of protein engineering." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 62, Issue Pt 5, pp. 457-9, (2006) (PubMed).

  • Target
    U2AF2 (U2AF59) (U2 Small Nuclear RNA Auxiliary Factor 2 (U2AF59))
    Andere Bezeichnung
    U2AF2 (U2AF59 Produkte)
    Synonyme
    U2AF65 antikoerper, 65kDa antikoerper, u2af65 antikoerper, U2AF2 antikoerper, DDBDRAFT_0186947 antikoerper, DDBDRAFT_0233353 antikoerper, DDB_0186947 antikoerper, DDB_0233353 antikoerper, zgc:110115 antikoerper, U2 small nuclear RNA auxiliary factor 2 antikoerper, U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2 antikoerper, U2 small nuclear RNA auxiliary factor 2 S homeolog antikoerper, RNA recognition motif-containing protein RRM antikoerper, Splicing factor U2AF 65 kDa subunit antikoerper, U2 small nuclear RNA auxiliary factor 2a antikoerper, U2AF2 antikoerper, U2af2 antikoerper, u2af2.S antikoerper, u2af2 antikoerper, u2af2a antikoerper
    Hintergrund
    U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2AF2 is the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly.U2 auxiliary factor (U2AF), comprised of a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. This gene encodes the U2AF large subunit which contains a sequence-specific RNA-binding region with 3 RNA recognition motifs and an Arg/Ser-rich domain necessary for splicing. The large subunit binds to the polypyrimidine tract of introns early during spliceosome assembly. Multiple transcript variants have been detected for this gene, but the full-length natures of only two have been determined to date.
    Alias Symbols: U2AF65
    Protein Interaction Partner: THAP1, PUF60, U2AF1, SNRPA, AES, DACH1, SUMO3, UBC, SUZ12, EED, TERF1, EZH2, RNF2, PRPF40A, TCERG1, APBB1, PIN1, SH3RF2, SRPK2, SRPK1, SF1, SRSF1, RBM39, QKI, SCAF11, PRPF3, RBM10, RBM4, SMAD5, IL7R, HNRNPK, HNRNPD, HLA-DMA, SUGP1, CCAR1, SAP30BP, RBFOX2,
    Protein Size: 471
    Molekulargewicht
    52 kDa
    Gen-ID
    11338
    NCBI Accession
    NM_001012478, NP_001012496
    UniProt
    Q96HC5
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