RED1 Antikörper (N-Term)

Produktnummer ABIN501953

Produktdetails anti-RED1 Antikörper

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NMSSSSTDVK ENRNLDNVSP KDGSTPGPGE GSQLSNGGGG GPGRKRPLEE

Homologie: Cow: 83%, Dog: 92%, Horse: 92%, Human: 100%, Mouse: 92%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against ADARB1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ADARB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 729 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RED1

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Andere Bezeichnung: ADARB1 (ADARB1 Produkte)

Hintergrund: ADARB1 is an enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
Alias Symbols: ADAR2, ADAR2a, ADAR2a-L1, ADAR2a-L2, ADAR2a-L3, ADAR2b, ADAR2d, ADAR2g, DRABA2, DRADA2, RED1
Protein Interaction Partner: EBNA1BP2, IFRD2, CCDC124, NIFK, C7orf50, C1orf35, STRBP, BRIX1, SDAD1, ZFR, NOP16, MRTO4, RRS1, BMI1, APP, UBC, PPP2CB, WWP2, PIN1,
Protein Size: 729

Molekulargewicht: 80 kDa

Gen-ID: 104

NCBI Accession: NM_001033049, NP_001028221

UniProt: P78563