CDC5L Antikörper (Middle Region)

Produktnummer ABIN2778760

Produktdetails anti-CDC5L Antikörper

Target: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Pferd, Kaninchen, Hund, Ziege, Meerschweinchen, Rind (Kuh), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDC5L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LHWYTGEGMD EMEFTEAESN MNDLVSEYQQ YQDATADEQG EFEEEEGEDE

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 90%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CDC5L. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDC5L

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 802 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CDC5L

Target: CDC5L (CDC5 Cell Division Cycle 5-Like (S. Pombe) (CDC5L))

Andere Bezeichnung: CDC5L (CDC5L Produkte)

Synonyme: zgc:55853 antikoerper, CDC5L antikoerper, CDC5 antikoerper, CDC5-LIKE antikoerper, CEF1 antikoerper, PCDC5RP antikoerper, dJ319D22.1 antikoerper, 1200002I02Rik antikoerper, AA408004 antikoerper, ARABIDOPSIS THALIANA CELL DIVISION CYCLE 5 antikoerper, ARABIDOPSIS THALIANA MYB DOMAIN CELL DIVISION CYCLE 5 antikoerper, ATCDC5 antikoerper, ATMYBCDC5 antikoerper, F21M12.15 antikoerper, F21M12_15 antikoerper, cell division cycle 5 antikoerper, CDC5 cell division cycle 5-like (S. pombe) antikoerper, cell division cycle 5 like antikoerper, cell division cycle 5-like antikoerper, cell division cycle 5 like S homeolog antikoerper, cell division cycle 5-like (S. pombe) antikoerper, cell division cycle 5 antikoerper, cdc5l antikoerper, CDC5L antikoerper, Chro.50385 antikoerper, Cdc5l antikoerper, cdc5l.S antikoerper, CDC5 antikoerper

Hintergrund: CDC5L shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. CDC5L has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CEF1, KIAA0432, PCDC5RP, dJ319D22.1, hCDC5, CDC5, CDC5-LIKE
Protein Interaction Partner: GOLGA2, FUS, GOLGA8F, GOLGA8EP, STAU1, UBC, LIN28A, RPA3, RPA2, RPA1, ERG, WWOX, TCP1, EED, rev, TARDBP, CSNK2A2, EMID1, CDT1, MCM10, BCAS2, GRB14, CDKN2A, CDKN1A, WHSC1, SMARCD1, ORC5, ORC2, ORC1, MCM5, MCM4, MCM3, LMO2, KRT18, EIF4A3, MAGOH, PAXIP1, MDC
Protein Size: 802

Molekulargewicht: 92 kDa

Gen-ID: 988

NCBI Accession: NM_001253, NP_001244

UniProt: Q99459

Pathways: Activation of Innate immune Response, Chromatin Binding