EIF4B Antikörper (C-Term)

Produktnummer ABIN2778771

Produktdetails anti-EIF4B Antikörper

Target: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: NPPARSQSSD TEQQSPTSGG GKVAPAQPSE EGPGRKDENK VDGMNAPKGQ

Homologie: Cow: 79%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 79%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF4B. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EIF4B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 611 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EIF4B Antikörper (ABIN2778771)

Suzuki, Fujisawa, Ando, Niino, Ohsawa, Shimokata, Ohta: "Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae." in: Neurology, Vol. 63, Issue 9, pp. 1711-3, (2004) (PubMed).

Details zu EIF4B

Target: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Andere Bezeichnung: EIF4B (EIF4B Produkte)

Synonyme: EIF-4B antikoerper, PRO1843 antikoerper, CG10837 antikoerper, Dm-eIF4B antikoerper, Dmel\\CG10837 antikoerper, Eif4B antikoerper, eIF-4B-L antikoerper, eIF-4B-S antikoerper, eIF-4b antikoerper, eIF4B antikoerper, eIF4B-L antikoerper, eIF4B-S antikoerper, eIf4b antikoerper, 2310046H11Rik antikoerper, AL024095 antikoerper, C85189 antikoerper, Eif4a2 antikoerper, eif4b antikoerper, fb15c09 antikoerper, wu:fb15c09 antikoerper, zgc:101532 antikoerper, MGC89384 antikoerper, eukaryotic translation initiation factor 4B antikoerper, eukaryotic initiation factor 4B antikoerper, Eukaryotic initiation factor 4B antikoerper, eukaryotic translation initiation factor 4Bb antikoerper, eukaryotic translation initiation factor 4Ba antikoerper, eukaryotic translation initiation factor 4B S homeolog antikoerper, EIF4B antikoerper, Eif4B antikoerper, eIF-4B antikoerper, Eif4b antikoerper, eif4bb antikoerper, eif4b antikoerper, eif4ba antikoerper, eif4b.S antikoerper, LOC100284982 antikoerper, LOC100380867 antikoerper

Hintergrund: IF4B contains 1 RRM (RNA recognition motif) domain and is required for the binding of mRNA to ribosomes. Functions of EIF4B are in close association with EEF4-F and EIF4-A. It binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP and promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.
Alias Symbols: EIF-4B, PRO1843
Protein Interaction Partner: UBC, ASB2, ZBTB1, SAMHD1, XPO7, SEC23A, PRMT3, CUL4B, USP11, SF1, XRCC5, OSBP, NARS, Stk11, CTNNA1, PARK2, FBXO6, PAN2, CSNK2A1, EIF4A3, YWHAE, MAGOH, SMURF1, NUP107, PHAX, SLC4A1AP, CCT6B, NUP153, POLR1C, RPL29, MYH9, EIF4G2, EIF4G1, EIF4A1, CSTF2, CUL3,
Protein Size: 611

Molekulargewicht: 67 kDa

Gen-ID: 1975

NCBI Accession: NM_001417, NP_001408

UniProt: P23588