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PIGF Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PIGF in IHC und WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein und Schaf und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2778804

Kurzübersicht für PIGF Antikörper (N-Term) (ABIN2778804)

Target

Alle PIGF Antikörper anzeigen
PIGF (Phosphatidylinositol Glycan F (PIGF))

Reaktivität

Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Schaf

Wirt

  • 8
Kaninchen

Klonalität

  • 8
Polyklonal

Konjugat

  • 8
Dieser PIGF Antikörper ist unkonjugiert

Applikation

  • 6
  • 5
  • 5
  • 1
  • 1
Immunohistochemistry (IHC), Western Blotting (WB)
  • Bindungsspezifität

    • 3
    • 2
    N-Term

    Sequenz

    MKDNDIKRLL YTHLLCIFSI ILSVFIPSLF LENFSILETH LTWLCICSGF

    Homologie

    Cow: 86%, Dog: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 86%, Sheep: 86%

    Produktmerkmale

    This is a rabbit polyclonal antibody against PIGF. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human PIGF
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 219 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Mohammed, Nasreen, Tepper, Antony: "Cyclic stretch induces PlGF expression in bronchial airway epithelial cells via nitric oxide release." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 2, pp. L559-66, (2007) (PubMed).

  • Target

    PIGF (Phosphatidylinositol Glycan F (PIGF))

    Andere Bezeichnung

    PIGF

    Hintergrund

    PIGF is a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. PIGF and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described.
    Alias Symbols: MGC32646, MGC33136
    Protein Interaction Partner: PIGO, PIGG,
    Protein Size: 219

    Molekulargewicht

    25 kDa

    Gen-ID

    5281

    NCBI Accession

    NM_002643, NP_002634

    UniProt

    Q07326

    Pathways

    Inositol Metabolic Process
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