PIGF Antikörper (N-Term)

Produktnummer ABIN2778804

Produktdetails anti-PIGF Antikörper

Target: PIGF (Phosphatidylinositol Glycan F (PIGF))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIGF Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Sequenz: MKDNDIKRLL YTHLLCIFSI ILSVFIPSLF LENFSILETH LTWLCICSGF

Homologie: Cow: 86%, Dog: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 86%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PIGF. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIGF

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 219 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PIGF Antikörper (ABIN2778804)

Mohammed, Nasreen, Tepper, Antony: "Cyclic stretch induces PlGF expression in bronchial airway epithelial cells via nitric oxide release." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 2, pp. L559-66, (2007) (PubMed).

Details zu PIGF

Target: PIGF (Phosphatidylinositol Glycan F (PIGF))

Andere Bezeichnung: PIGF (PIGF Produkte)

Synonyme: pigf antikoerper, zgc:77184 antikoerper, phosphatidylinositol glycan anchor biosynthesis class F antikoerper, phosphatidylinositol glycan anchor biosynthesis, class F antikoerper, phosphatidylinositol glycan anchor biosynthesis class F S homeolog antikoerper, PIGF antikoerper, Pigf antikoerper, pigf.S antikoerper, pigf antikoerper

Hintergrund: PIGF is a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. PIGF and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: MGC32646, MGC33136
Protein Interaction Partner: PIGO, PIGG,
Protein Size: 219

Molekulargewicht: 25 kDa

Gen-ID: 5281

NCBI Accession: NM_002643, NP_002634

UniProt: Q07326

Pathways: Inositol Metabolic Process