RDBP Antikörper (N-Term)

Produktnummer ABIN2778822

Produktdetails anti-RDBP Antikörper

Target: RDBP (RD RNA Binding Protein (RDBP))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RDBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LVIPPGLSEE EEALQKKFNK LKKKKKALLA LKKQSSSSTT SQGGVKRSLS

Homologie: Cow: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against RDBP. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RDBP

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 380 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RDBP Antikörper (ABIN2778822)

Schulz, Brandner, Eberhagen, Eckardt-Schupp, Larsen, Andrae: "Quantitative phosphoproteomic analysis of early alterations in protein phosphorylation by 2,3,7,8-tetrachlorodibenzo-p-dioxin." in: Journal of proteome research, Vol. 12, Issue 2, pp. 866-82, (2013) (PubMed).

Details zu RDBP

Target: RDBP (RD RNA Binding Protein (RDBP))

Andere Bezeichnung: RDBP (RDBP Produkte)

Synonyme: CG5994 antikoerper, Dmel\\CG5994 antikoerper, NELF antikoerper, NELF-E antikoerper, Nelf-e antikoerper, anon-66Da antikoerper, cg5994 antikoerper, dNelf-E antikoerper, D6S45 antikoerper, RD antikoerper, RDBP antikoerper, RDP antikoerper, Rd antikoerper, Rdbp antikoerper, D17H6S45 antikoerper, Negative elongation factor E antikoerper, negative elongation factor complex member E antikoerper, negative elongation factor complex member E, Rdbp antikoerper, Nelf-E antikoerper, NELFE antikoerper, Nelfe antikoerper

Hintergrund: RDBP is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins, however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D).The protein encoded by this gene is part of a complex termed negative elongation factor (NELF) which represses RNA polymerase II transcript elongation. This protein bears similarity to nuclear RNA-binding proteins, however, it has not been demonstrated that this protein binds RNA. The protein contains a tract of alternating basic and acidic residues, largely arginine (R) and aspartic acid (D). The gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: D6S45, NELF-E, RD, RDP, RDBP
Protein Interaction Partner: CCDC57, MTUS2, TRIM27, UBC, SRPK2, SRPK1, LMNA, POLR2C, SUMO1, NELFCD, NELFB, SF3B1, NELFA, TMEM141, RPAP2, WDR48, VAMP3, NCOR1, NELFE, POLR2A, CACTIN,
Protein Size: 380

Molekulargewicht: 43 kDa

Gen-ID: 7936

NCBI Accession: NM_002904, NP_002895

UniProt: P18615