SNRNP70 Antikörper (C-Term)

Produktnummer ABIN2778829

Produktdetails anti-SNRNP70 Antikörper

Target: SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNRNP70 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RERERKEELR GGGGDMAEPS EAGDAPPDDG PPGELGPDGP DGPEEKGRDR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SNRP70. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human SNRP70

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 437 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SNRNP70 Antikörper (ABIN2778829)

Franklin, Chen, Mitchell-Jordan, Ren, Wang, Vondriska: "Quantitative analysis of the chromatin proteome in disease reveals remodeling principles and identifies high mobility group protein B2 as a regulator of hypertrophic growth." in: Molecular & cellular proteomics : MCP, Vol. 11, Issue 6, pp. M111.014258, (2012) (PubMed).

Serini, Fasano, Piccioni, Monego, Cittadini, Celleno, Ranelletti, Calviello: "DHA induces apoptosis and differentiation in human melanoma cells in vitro: involvement of HuR-mediated COX-2 mRNA stabilization and ?-catenin nuclear translocation." in: Carcinogenesis, Vol. 33, Issue 1, pp. 164-73, (2011) (PubMed).

Franklin, Zhang, Chen, Paulsson, Mitchell-Jordan, Li, Ping, Vondriska: "Specialized compartments of cardiac nuclei exhibit distinct proteomic anatomy." in: Molecular & cellular proteomics : MCP, Vol. 10, Issue 1, pp. M110.000703, (2011) (PubMed).

Details zu SNRNP70

Target: SNRNP70 (Small Nuclear Ribonucleoprotein 70kDa (U1) (SNRNP70))

Andere Bezeichnung: SNRP70 (SNRNP70 Produkte)

Synonyme: rnpu1z antikoerper, rpu1 antikoerper, snrp70 antikoerper, u170k antikoerper, u1ap antikoerper, u1rnp antikoerper, SNRP70 antikoerper, wu:fc20b04 antikoerper, zgc:136450 antikoerper, 2700022N21Rik antikoerper, 3200002N22Rik antikoerper, 70kDa antikoerper, AI325098 antikoerper, R74807 antikoerper, Rnulp70 antikoerper, Snrp70 antikoerper, Srnp70 antikoerper, U1-70 antikoerper, U1-70K antikoerper, RNPU1Z antikoerper, RPU1 antikoerper, Snp1 antikoerper, U170K antikoerper, U1AP antikoerper, U1RNP antikoerper, small nuclear ribonucleoprotein, U1 70kDa subunit antikoerper, small nuclear ribonucleoprotein U1 subunit 70 antikoerper, small nuclear ribonucleoprotein 70 (U1) antikoerper, small nuclear ribonucleoprotein, U1 70kDa subunit L homeolog antikoerper, snrnp70 antikoerper, SNRNP70 antikoerper, Snrnp70 antikoerper, snrnp70.L antikoerper

Hintergrund: SNRP70 contains 1 RRM (RNA recognition motif) domain and mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.
Alias Symbols: RNPU1Z, RPU1, U170K, U1AP, U1RNP, Snp1, SNRP70, U1-70K
Protein Interaction Partner: IL32, UBC, NEDD8, LIN28A, EZH2, SUZ12, EED, RNF2, rev, WBP4, SRPK2, SRPK1, MYC, SRPK3, HDAC2, PAN2, SMURF2, PRPF40A, CDKL3, RNF11, PRKD2, SKIL, RELA, RASGRF1, SMAD9, SMAD5, SMAD4, SMAD3, SMAD2, CHERP, PRMT5, UBL4A, VCAM1, SMAD1, ITGA4, IL7R, IFIT3, IFIT1,
Protein Size: 437

Molekulargewicht: 51 kDa

Gen-ID: 6625

NCBI Accession: NM_003089, NP_003080

UniProt: P08621