SNRPB Antikörper (Middle Region)

Produktnummer ABIN2778832

Produktdetails anti-SNRPB Antikörper

Target: SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SNRPB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LRGENLVSMT VEGPPPKDTG IARVPLAGAA GGPGIGRAAG RGIPAGVPMP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SNRPB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SNRPB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 231 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SNRPB

Target: SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))

Andere Bezeichnung: SNRPB (SNRPB Produkte)

Hintergrund: SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
Alias Symbols: COD, SNRPB1, SmB/SmB', snRNP-B, SmB/B', Sm-B/B'
Protein Interaction Partner: RFX6, KRT40, L3MBTL3, GOLGA2, DAB1, TRIM23, CEP55, BANP, SS18L1, TFIP11, RBPMS, CD2BP2, CALCOCO2, HUWE1, PNMA1, PSMA3, UBC, LIN28A, MEPCE, RPA3, RPA2, RPA1, SF3A3, NCS1, CDKN2A, SRPK3, PRPF4B, SRPK2, SKIV2L, ICAM1, CD81, IGSF8, PAN2, Snrpc, LSM8, SNRPD3,
Protein Size: 231

Molekulargewicht: 24 kDa

Gen-ID: 6628

NCBI Accession: NM_003091, NP_003082

UniProt: Q66K91

Pathways: Ribonucleoprotein Complex Subunit Organization