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XPO1 Antikörper (C-Term)

XPO1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio), Kaninchen, Schwein, Saccharomyces cerevisiae WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2778849
  • Target Alle XPO1 Antikörper anzeigen
    XPO1 (Exportin 1 (XPO1))
    Bindungsspezifität
    • 15
    • 10
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 72
    • 36
    • 35
    • 7
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio), Kaninchen, Schwein, Saccharomyces cerevisiae
    Wirt
    • 66
    • 6
    Kaninchen
    Klonalität
    • 57
    • 15
    Polyklonal
    Konjugat
    • 39
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser XPO1 Antikörper ist unkonjugiert
    Applikation
    • 45
    • 16
    • 15
    • 14
    • 14
    • 13
    • 8
    • 7
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    NKLGGHITAE IPQIFDAVFE CTLNMINKDF EEYPEHRTNF FLLLQAVNSH
    Homologie
    Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against XPO1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human XPO1
    Top Product
    Discover our top product XPO1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 1071 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Kalita, Kapinos, Zheng, Rencurel, Zilman, Lim: "Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage." in: The Journal of cell biology, Vol. 221, Issue 3, (2022) (PubMed).

  • Target
    XPO1 (Exportin 1 (XPO1))
    Andere Bezeichnung
    XPO1 (XPO1 Produkte)
    Synonyme
    CG13387 antikoerper, CRM1 antikoerper, Crm1 antikoerper, DCRM1 antikoerper, Dmel\\CG13387 antikoerper, Emb antikoerper, XPO-1 antikoerper, XPO1 antikoerper, Xpo1 antikoerper, crm1 antikoerper, dCRM1 antikoerper, l(2)k16715 antikoerper, 18.m06600 antikoerper, DDBDRAFT_0183812 antikoerper, DDBDRAFT_0234066 antikoerper, DDB_0183812 antikoerper, DDB_0234066 antikoerper, exportin-1 antikoerper, LOC100220104 antikoerper, emb antikoerper, exp1 antikoerper, Xpo antikoerper, AA420417 antikoerper, Exp1 antikoerper, embargoed antikoerper, exportin 1 antikoerper, putative exportin 1 antikoerper, chromosome region maintenance protein 1 antikoerper, exportin-1 antikoerper, exportin 1 (CRM1 homolog, yeast) antikoerper, exportin 1 S homeolog antikoerper, emb antikoerper, cgd3_3060 antikoerper, Tc00.1047053511725.150 antikoerper, Tb11.01.5940 antikoerper, BBOV_II007220 antikoerper, LMJF_32_1100 antikoerper, xpo1 antikoerper, Xpo1 antikoerper, XPO1 antikoerper, LOC100165622 antikoerper, LOC100633509 antikoerper, xpo1.S antikoerper
    Hintergrund
    XPO1 mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. XPO1 also regulates NFAT and AP-1.The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: CRM1, DKFZp686B1823, emb, exp1
    Protein Interaction Partner: ABL1, UBC, HUWE1, ELAVL1, KEAP1, SUMO2, SUMO3, USP16, STAU1, CDC37L1, RNF2, rev, TUBB, SCPEP1, CAMK1D, DCPS, HSPA1L, HNRNPK, GNAI3, EEF2, CAPN2, TWF2, FERMT2, UBA3, NAE1, STK24, YWHAH, YWHAE, VCL, TUFM, PCYT2, PPP5C, PPP1CA, EGFR, LOC366310, CLN5, CLN3, S
    Protein Size: 1071
    Molekulargewicht
    123 kDa
    Gen-ID
    7514
    NCBI Accession
    NM_003400, NP_003391
    UniProt
    O14980
    Pathways
    M Phase
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